SaLT&PepPr is an interface-predicting language model for designing peptide-guided protein degraders

Protein-protein interactions (PPIs) are critical for biological processes and predicting the sites of these interactions is useful for both computational and experimental applications. We present a Structure-agnostic Language Transformer and Peptide Prioritization (SaLT&PepPr) pipeline to predic...

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Detalles Bibliográficos
Autores principales: Brixi, Garyk, Ye, Tianzheng, Hong, Lauren, Wang, Tian, Monticello, Connor, Lopez-Barbosa, Natalia, Vincoff, Sophia, Yudistyra, Vivian, Zhao, Lin, Haarer, Elena, Chen, Tianlai, Pertsemlidis, Sarah, Palepu, Kalyan, Bhat, Suhaas, Christopher, Jayani, Li, Xinning, Liu, Tong, Zhang, Sue, Petersen, Lillian, DeLisa, Matthew P., Chatterjee, Pranam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598214/
https://www.ncbi.nlm.nih.gov/pubmed/37875551
http://dx.doi.org/10.1038/s42003-023-05464-z

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