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Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report
BACKGROUND: Chondrosarcomas are an exceedingly rare form of cancer, impacting only a few individuals per million. Among chondrosarcomas, a small fraction belongs to the mesenchymal sub‐type. Furthermore, only one‐third of mesenchymal chondrosarcomas manifest in extraskeletal locations. CASE: A 38‐ye...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598256/ https://www.ncbi.nlm.nih.gov/pubmed/37559178 http://dx.doi.org/10.1002/cnr2.1883 |
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author | Shahnazari, Razieh Montazer, Fatemeh Shirzadi, Shahriar Karaji, Sina |
author_facet | Shahnazari, Razieh Montazer, Fatemeh Shirzadi, Shahriar Karaji, Sina |
author_sort | Shahnazari, Razieh |
collection | PubMed |
description | BACKGROUND: Chondrosarcomas are an exceedingly rare form of cancer, impacting only a few individuals per million. Among chondrosarcomas, a small fraction belongs to the mesenchymal sub‐type. Furthermore, only one‐third of mesenchymal chondrosarcomas manifest in extraskeletal locations. CASE: A 38‐year‐old woman was referred by a midwife after experiencing pain in the right upper quadrant of her right breast for 2 months. The mass had been palpable for 1 week before the initial assessment. According to radiological evaluations, the tumor is outside breast tissue and not connected to the bones. Hence, a biopsy of the mass is done. The biphasic morphology of the tumor during pathological evaluation, in addition to immunohistochemistry testing, confirms the diagnosis of extraskeletal mesenchymal chondrosarcoma (EMCS). Finally, the mass was surgically removed, and 6 months of chemotherapy were administered to the patient. CONCLUSION: Given the tumor's rarity and the lack of established guidelines, diagnosing EMCS can be challenging and prone to errors. As such, meticulous sampling, along with precise pathological and imaging investigations, is imperative to accurately establish the diagnosis of these tumors. |
format | Online Article Text |
id | pubmed-10598256 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105982562023-10-26 Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report Shahnazari, Razieh Montazer, Fatemeh Shirzadi, Shahriar Karaji, Sina Cancer Rep (Hoboken) Case Reports BACKGROUND: Chondrosarcomas are an exceedingly rare form of cancer, impacting only a few individuals per million. Among chondrosarcomas, a small fraction belongs to the mesenchymal sub‐type. Furthermore, only one‐third of mesenchymal chondrosarcomas manifest in extraskeletal locations. CASE: A 38‐year‐old woman was referred by a midwife after experiencing pain in the right upper quadrant of her right breast for 2 months. The mass had been palpable for 1 week before the initial assessment. According to radiological evaluations, the tumor is outside breast tissue and not connected to the bones. Hence, a biopsy of the mass is done. The biphasic morphology of the tumor during pathological evaluation, in addition to immunohistochemistry testing, confirms the diagnosis of extraskeletal mesenchymal chondrosarcoma (EMCS). Finally, the mass was surgically removed, and 6 months of chemotherapy were administered to the patient. CONCLUSION: Given the tumor's rarity and the lack of established guidelines, diagnosing EMCS can be challenging and prone to errors. As such, meticulous sampling, along with precise pathological and imaging investigations, is imperative to accurately establish the diagnosis of these tumors. John Wiley and Sons Inc. 2023-08-09 /pmc/articles/PMC10598256/ /pubmed/37559178 http://dx.doi.org/10.1002/cnr2.1883 Text en © 2023 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Shahnazari, Razieh Montazer, Fatemeh Shirzadi, Shahriar Karaji, Sina Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report |
title | Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report |
title_full | Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report |
title_fullStr | Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report |
title_full_unstemmed | Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report |
title_short | Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report |
title_sort | extraskeletal mesenchymal chondrosarcoma arising from soft tissues: a rare case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598256/ https://www.ncbi.nlm.nih.gov/pubmed/37559178 http://dx.doi.org/10.1002/cnr2.1883 |
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