Quinoxalines against Leishmania amazonensis: SAR study, proposition of a new derivative, QSAR prediction, synthesis, and biological evaluation

Neglected tropical diseases, such as leishmaniasis, lead to serious limitations to the affected societies. In this work, a structure–activity relationship (SAR) study was developed with a series of quinoxaline derivatives, active against the promastigote forms of Leishmania amazonensis. As a result,...

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Detalles Bibliográficos
Autores principales: Silva de Jesus Passaes, Anna Carolina, Arantes Dantas, Juliana, Landim Lopes, Fernanda, Pereira Sangi, Diego, Girão Albuquerque, Magaly, Vataru Nakamura, Celso, Yoneda, Julliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598266/
https://www.ncbi.nlm.nih.gov/pubmed/37875605
http://dx.doi.org/10.1038/s41598-023-45436-1

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