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Interpretable spatial identity neural network-based epidemic prediction

Epidemic spatial–temporal risk analysis, e.g., infectious number forecasting, is a mainstream task in the multivariate time series research field, which plays a crucial role in the public health management process. With the rise of deep learning methods, many studies have focused on the epidemic pre...

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Autores principales: Luo, Lanjun, Li, Boxiao, Wang, Xueyan, Cui, Lei, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598274/
https://www.ncbi.nlm.nih.gov/pubmed/37875546
http://dx.doi.org/10.1038/s41598-023-45177-1
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author Luo, Lanjun
Li, Boxiao
Wang, Xueyan
Cui, Lei
Liu, Gang
author_facet Luo, Lanjun
Li, Boxiao
Wang, Xueyan
Cui, Lei
Liu, Gang
author_sort Luo, Lanjun
collection PubMed
description Epidemic spatial–temporal risk analysis, e.g., infectious number forecasting, is a mainstream task in the multivariate time series research field, which plays a crucial role in the public health management process. With the rise of deep learning methods, many studies have focused on the epidemic prediction problem. However, recent primary prediction techniques face two challenges: the overcomplicated model and unsatisfactory interpretability. Therefore, this paper proposes an Interpretable Spatial IDentity (ISID) neural network to predict infectious numbers at the regional weekly level, which employs a light model structure and provides post-hoc explanations. First, this paper streamlines the classical spatio-temporal identity model (STID) and retains the optional spatial identity matrix for learning the contagion relationship between regions. Second, the well-known SHapley Additive explanations (SHAP) method was adopted to interpret how the ISID model predicts with multivariate sliding-window time series input data. The prediction accuracy of ISID is compared with several models in the experimental study, and the results show that the proposed ISID model achieves satisfactory epidemic prediction performance. Furthermore, the SHAP result demonstrates that the ISID pays particular attention to the most proximate and remote data in the input sequence (typically 20 steps long) while paying little attention to the intermediate steps. This study contributes to reliable and interpretable epidemic prediction through a more coherent approach for public health experts.
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spelling pubmed-105982742023-10-26 Interpretable spatial identity neural network-based epidemic prediction Luo, Lanjun Li, Boxiao Wang, Xueyan Cui, Lei Liu, Gang Sci Rep Article Epidemic spatial–temporal risk analysis, e.g., infectious number forecasting, is a mainstream task in the multivariate time series research field, which plays a crucial role in the public health management process. With the rise of deep learning methods, many studies have focused on the epidemic prediction problem. However, recent primary prediction techniques face two challenges: the overcomplicated model and unsatisfactory interpretability. Therefore, this paper proposes an Interpretable Spatial IDentity (ISID) neural network to predict infectious numbers at the regional weekly level, which employs a light model structure and provides post-hoc explanations. First, this paper streamlines the classical spatio-temporal identity model (STID) and retains the optional spatial identity matrix for learning the contagion relationship between regions. Second, the well-known SHapley Additive explanations (SHAP) method was adopted to interpret how the ISID model predicts with multivariate sliding-window time series input data. The prediction accuracy of ISID is compared with several models in the experimental study, and the results show that the proposed ISID model achieves satisfactory epidemic prediction performance. Furthermore, the SHAP result demonstrates that the ISID pays particular attention to the most proximate and remote data in the input sequence (typically 20 steps long) while paying little attention to the intermediate steps. This study contributes to reliable and interpretable epidemic prediction through a more coherent approach for public health experts. Nature Publishing Group UK 2023-10-24 /pmc/articles/PMC10598274/ /pubmed/37875546 http://dx.doi.org/10.1038/s41598-023-45177-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Luo, Lanjun
Li, Boxiao
Wang, Xueyan
Cui, Lei
Liu, Gang
Interpretable spatial identity neural network-based epidemic prediction
title Interpretable spatial identity neural network-based epidemic prediction
title_full Interpretable spatial identity neural network-based epidemic prediction
title_fullStr Interpretable spatial identity neural network-based epidemic prediction
title_full_unstemmed Interpretable spatial identity neural network-based epidemic prediction
title_short Interpretable spatial identity neural network-based epidemic prediction
title_sort interpretable spatial identity neural network-based epidemic prediction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598274/
https://www.ncbi.nlm.nih.gov/pubmed/37875546
http://dx.doi.org/10.1038/s41598-023-45177-1
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