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Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel

INTRODUCTION: Nerium oleander is a toxic plant containing cardiac glycosides throughout all its parts, thereby posing severe health risks upon ingestion. The clinical manifestations of oleander poisoning closely resemble those of digoxin toxicity, encompassing a spectrum of gastrointestinal symptoms...

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Autores principales: Mantelli, Giovanni, Carollo, Massimo, Losso, Lorenzo, Costantini, Ilaria, Morando, Elia, Bacchion, Matilde, Pizzuto, Mauro, Spagnuolo, Letizia, Ricci, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598396/
https://www.ncbi.nlm.nih.gov/pubmed/37885923
http://dx.doi.org/10.1016/j.toxrep.2023.10.010
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author Mantelli, Giovanni
Carollo, Massimo
Losso, Lorenzo
Costantini, Ilaria
Morando, Elia
Bacchion, Matilde
Pizzuto, Mauro
Spagnuolo, Letizia
Ricci, Giorgio
author_facet Mantelli, Giovanni
Carollo, Massimo
Losso, Lorenzo
Costantini, Ilaria
Morando, Elia
Bacchion, Matilde
Pizzuto, Mauro
Spagnuolo, Letizia
Ricci, Giorgio
author_sort Mantelli, Giovanni
collection PubMed
description INTRODUCTION: Nerium oleander is a toxic plant containing cardiac glycosides throughout all its parts, thereby posing severe health risks upon ingestion. The clinical manifestations of oleander poisoning closely resemble those of digoxin toxicity, encompassing a spectrum of gastrointestinal symptoms, neuropsychiatric disorders, and cardiac disturbances. This scientific case report describes a case of accidental intoxication resulting from the consumption of an oleander leaves infusion misidentified as bay laurel leaves. CASE REPORT: An 84-year-old patient consumed an oleander leaves infusion, and after four hours experienced gastrointestinal symptoms. He contacted the poison control center (PCC) and was advised to go to the emergency department (ED). Upon arrival, the patient presented stable vital signs without cardiac irregularities. The PCC recommended the administration of activated charcoal, vigilant monitoring, including electrocardiography (ECG). Subsequent ECGs assessments revealed the presence of third-degree atrioventricular block; in consultation with the PCC, digoxin-specific antibodies and external pacing were necessary. The patient was discharged on the eighth day in good hemodynamic condition, and outpatient follow-up visits showed clinical stability. DISCUSSION: This study offers insights for the management of similar cases. The limitations of conventional assays in measuring oleander cardiac glycosides were observed, emphasizing reliance on clinical evaluation. The patient's trajectory, remaining asymptomatic despite severe ECG changes post-ingestion, underscores the importance of prolonged clinical monitoring.
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spelling pubmed-105983962023-10-26 Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel Mantelli, Giovanni Carollo, Massimo Losso, Lorenzo Costantini, Ilaria Morando, Elia Bacchion, Matilde Pizzuto, Mauro Spagnuolo, Letizia Ricci, Giorgio Toxicol Rep Article INTRODUCTION: Nerium oleander is a toxic plant containing cardiac glycosides throughout all its parts, thereby posing severe health risks upon ingestion. The clinical manifestations of oleander poisoning closely resemble those of digoxin toxicity, encompassing a spectrum of gastrointestinal symptoms, neuropsychiatric disorders, and cardiac disturbances. This scientific case report describes a case of accidental intoxication resulting from the consumption of an oleander leaves infusion misidentified as bay laurel leaves. CASE REPORT: An 84-year-old patient consumed an oleander leaves infusion, and after four hours experienced gastrointestinal symptoms. He contacted the poison control center (PCC) and was advised to go to the emergency department (ED). Upon arrival, the patient presented stable vital signs without cardiac irregularities. The PCC recommended the administration of activated charcoal, vigilant monitoring, including electrocardiography (ECG). Subsequent ECGs assessments revealed the presence of third-degree atrioventricular block; in consultation with the PCC, digoxin-specific antibodies and external pacing were necessary. The patient was discharged on the eighth day in good hemodynamic condition, and outpatient follow-up visits showed clinical stability. DISCUSSION: This study offers insights for the management of similar cases. The limitations of conventional assays in measuring oleander cardiac glycosides were observed, emphasizing reliance on clinical evaluation. The patient's trajectory, remaining asymptomatic despite severe ECG changes post-ingestion, underscores the importance of prolonged clinical monitoring. Elsevier 2023-10-21 /pmc/articles/PMC10598396/ /pubmed/37885923 http://dx.doi.org/10.1016/j.toxrep.2023.10.010 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Mantelli, Giovanni
Carollo, Massimo
Losso, Lorenzo
Costantini, Ilaria
Morando, Elia
Bacchion, Matilde
Pizzuto, Mauro
Spagnuolo, Letizia
Ricci, Giorgio
Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel
title Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel
title_full Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel
title_fullStr Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel
title_full_unstemmed Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel
title_short Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel
title_sort laurel but hardy: unintended poisoning, a case report of oleander misidentification as bay laurel
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598396/
https://www.ncbi.nlm.nih.gov/pubmed/37885923
http://dx.doi.org/10.1016/j.toxrep.2023.10.010
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