Cardiomyocyte NOX4 regulates resident macrophage-mediated inflammation and diastolic dysfunction in stress cardiomyopathy

In acute sympathetic stress, catecholamine overload can lead to stress cardiomyopathy. We tested the hypothesis that cardiomyocyte NOX4 (NADPH oxidase 4)-dependent mitochondrial oxidative stress mediates inflammation and diastolic dysfunction in stress cardiomyopathy. Isoproterenol (ISO; 5 mg/kg) in...

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Detalles Bibliográficos
Autores principales: Vendrov, Aleksandr E., Xiao, Han, Lozhkin, Andrey, Hayami, Takayuki, Hu, Guomin, Brody, Matthew J., Sadoshima, Junichi, Zhang, You-Yi, Runge, Marschall S., Madamanchi, Nageswara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598408/
https://www.ncbi.nlm.nih.gov/pubmed/37871532
http://dx.doi.org/10.1016/j.redox.2023.102937

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