Cargando…

Possible contribution of rare alleles of human ACE2 in the emergence of SARS-CoV-2 variants escaping the immune response

Since the start of the SARS-CoV-2 pandemic, the rapid replacement of one lineage by another has been observed. Indeed, SARS-CoV-2 is evolving through a quasispecies mechanism leading to post-infection mutation selection under positive evolutionary pressure (host-driven viral evolution). These mutati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Devaux, Christian A., Fantini, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598458/ https://www.ncbi.nlm.nih.gov/pubmed/37885880 http://dx.doi.org/10.3389/fimmu.2023.1252367

Ejemplares similares

ACE2 receptor polymorphism in humans and animals increases the risk of the emergence of SARS-CoV-2 variants during repeated intra- and inter-species host-switching of the virus
por: Devaux, Christian A., et al.
Publicado: (2023)

A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations
por: Chakraborty, Chiranjib, et al.
Publicado: (2022)

Omicron: A Heavily Mutated SARS-CoV-2 Variant Exhibits Stronger Binding to ACE2 and Potently Escapes Approved COVID-19 Therapeutic Antibodies
por: Shah, Masaud, et al.
Publicado: (2022)

Understanding the Secret of SARS-CoV-2 Variants of Concern/Interest and Immune Escape
por: Lou, Fuxing, et al.
Publicado: (2021)

CD8(+) T-cell immune escape by SARS-CoV-2 variants of concern
por: Kombe Kombe, Arnaud John, et al.
Publicado: (2022)

The Global Epidemic of the SARS-CoV-2 Delta Variant, Key Spike Mutations and Immune Escape
por: Tian, Dandan, et al.
Publicado: (2021)

Implication of SARS-CoV-2 Immune Escape Spike Variants on Secondary and Vaccine Breakthrough Infections
por: Ahmad, Liyana
Publicado: (2021)

SARS-CoV-2 Omicron Variants Reduce Antibody Neutralization and Acquire Usage of Mouse ACE2
por: Wang, Ruoke, et al.
Publicado: (2022)

Novel ACE2 fusion protein with adapting activity against SARS-CoV-2 variants in vitro
por: Zekri, Latifa, et al.
Publicado: (2023)

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
por: Weisblum, Yiska, et al.
Publicado: (2020)

A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells
por: Kegler, Alexandra, et al.
Publicado: (2023)

ACE and ACE2 Gene Variants Are Associated With Severe Outcomes of COVID-19 in Men
por: Martínez-Gómez, Laura E., et al.
Publicado: (2022)

Pan-neutralizing, germline-encoded antibodies against SARS-CoV-2: Addressing the long-term problem of escape variants
por: Lunderberg, Justin Mark, et al.
Publicado: (2022)

ACE2-Fc fusion protein overcomes viral escape by potently neutralizing SARS-CoV-2 variants of concern
por: Tsai, Tsung-I, et al.
Publicado: (2022)

Rational strategies for enhancing mAb binding to SARS-CoV-2 variants through CDR diversification and antibody-escape prediction
por: Shah, Masaud, et al.
Publicado: (2023)

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2
por: Higuchi, Yusuke, et al.
Publicado: (2021)

Decoy ACE2-expressing extracellular vesicles that competitively bind SARS-CoV-2 as a possible COVID-19 therapy
por: Inal, Jameel M.
Publicado: (2020)

Broadly-Neutralizing Antibodies Against Emerging SARS-CoV-2 Variants
por: Shrestha, Lok Bahadur, et al.
Publicado: (2021)

The impact of cross-reactive immunity on the emergence of SARS-CoV-2 variants
por: Thompson, Robin N., et al.
Publicado: (2023)

Molecular and Epidemiological Characterization of Emerging Immune-Escape Variants of SARS-CoV-2
por: Miyakawa, Kei, et al.
Publicado: (2022)

Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients
por: Osman, Ikram Omar, et al.
Publicado: (2021)

Early pathogenesis profiles across SARS-CoV-2 variants in K18-hACE2 mice revealed differential triggers of lung damages
por: Aw, Zhen Qin, et al.
Publicado: (2022)

Pathophysiological conditions induced by SARS-CoV-2 infection reduce ACE2 expression in the lung
por: Miura, Yoko, et al.
Publicado: (2022)

Crucial Mutations of Spike Protein on SARS-CoV-2 Evolved to Variant Strains Escaping Neutralization of Convalescent Plasmas and RBD-Specific Monoclonal Antibodies
por: Ding, Chengchao, et al.
Publicado: (2021)

Insight into SARS-CoV-2 Omicron variant immune escape possibility and variant independent potential therapeutic opportunities
por: Alam, Mohammad Shah
Publicado: (2023)

Fighting the Host Reaction to SARS-COv-2 in Critically Ill Patients: The Possible Contribution of Off-Label Drugs
por: Scala, Stefania, et al.
Publicado: (2020)

Passive immunization with equine RBD-specific Fab protects K18-hACE2-mice against Alpha or Beta variants of SARS-CoV-2
por: Barbier, Mariette, et al.
Publicado: (2022)

Equine Anti-SARS-CoV-2 Serum (ECIG) Binds to Mutated RBDs and N Proteins of Variants of Concern and Inhibits the Binding of RBDs to ACE-2 Receptor
por: Andrade, Sonia Aparecida, et al.
Publicado: (2022)

Glucocorticoids Bind to SARS-CoV-2 S1 at Multiple Sites Causing Cooperative Inhibition of SARS-CoV-2 S1 Interaction With ACE2
por: Sarker, Hassan, et al.
Publicado: (2022)

Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2
por: Lai, Yen-Chung, et al.
Publicado: (2022)

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2
por: Wines, Bruce D., et al.
Publicado: (2022)

Galectin-9 protects humanized-ACE2 immunocompetent mice from SARS-CoV-2 infection
por: Yeung, Stephen T., et al.
Publicado: (2022)

Conservation and Evolution of Antigenic Determinants of SARS-CoV-2: An Insight for Immune Escape and Vaccine Design
por: Jaiswal, Varun, et al.
Publicado: (2022)

Targeted escape of SARS-CoV-2 in vitro from monoclonal antibody S309, the precursor of sotrovimab
por: Magnus, Clara Luzia, et al.
Publicado: (2022)

Molecular Mimicry of the Viral Spike in the SARS-CoV-2 Vaccine Possibly Triggers Transient Dysregulation of ACE2, Leading to Vascular and Coagulation Dysfunction Similar to SARS-CoV-2 Infection
por: Devaux, Christian A., et al.
Publicado: (2023)

SARS-CoV-2 variants, immune escape, and countermeasures
por: Zhang, Yi, et al.
Publicado: (2022)

A Possible Role of Remdesivir and Plasma Therapy in the Selective Sweep and Emergence of New SARS-CoV-2 Variants
por: Colson, Philippe, et al.
Publicado: (2021)

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species
por: Wang, Ruoke, et al.
Publicado: (2021)

Escape of SARS-CoV-2 Variant Omicron to Mucosal Immunity in Vaccinated Subjects
por: Martinuzzi, Emanuela, et al.
Publicado: (2022)

Corrigendum: Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2
por: Wines, Bruce D., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p5rogiv4fs93pe2dk42ollg9at