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Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogene...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598475/ https://www.ncbi.nlm.nih.gov/pubmed/37886048 http://dx.doi.org/10.3389/fpubh.2023.1232646 |
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author | Lahimer, Marwa Abou Diwan, Maria Montjean, Debbie Cabry, Rosalie Bach, Véronique Ajina, Mounir Ben Ali, Habib Benkhalifa, Moncef Khorsi-Cauet, Hafida |
author_facet | Lahimer, Marwa Abou Diwan, Maria Montjean, Debbie Cabry, Rosalie Bach, Véronique Ajina, Mounir Ben Ali, Habib Benkhalifa, Moncef Khorsi-Cauet, Hafida |
author_sort | Lahimer, Marwa |
collection | PubMed |
description | The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogenesis, the maturation and competency of gametes and has guided scientists to hypothesize that endocrine disrupting chemicals (EDCs) may disrupt hormonal homoeostasis by leading to a wide range of hormonal control impairments. The effects of EDCs exposure on reproductive health are highly dependent on factors including the type of EDCs, the duration of exposure, individual susceptibility, and the presence of other co-factors. Research and scientists continue to study these complex interactions. The aim of this review is to summarize the literature to better understand the potential reproductive health risks of EDCs in France. |
format | Online Article Text |
id | pubmed-10598475 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105984752023-10-26 Endocrine disrupting chemicals and male fertility: from physiological to molecular effects Lahimer, Marwa Abou Diwan, Maria Montjean, Debbie Cabry, Rosalie Bach, Véronique Ajina, Mounir Ben Ali, Habib Benkhalifa, Moncef Khorsi-Cauet, Hafida Front Public Health Public Health The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogenesis, the maturation and competency of gametes and has guided scientists to hypothesize that endocrine disrupting chemicals (EDCs) may disrupt hormonal homoeostasis by leading to a wide range of hormonal control impairments. The effects of EDCs exposure on reproductive health are highly dependent on factors including the type of EDCs, the duration of exposure, individual susceptibility, and the presence of other co-factors. Research and scientists continue to study these complex interactions. The aim of this review is to summarize the literature to better understand the potential reproductive health risks of EDCs in France. Frontiers Media S.A. 2023-10-10 /pmc/articles/PMC10598475/ /pubmed/37886048 http://dx.doi.org/10.3389/fpubh.2023.1232646 Text en Copyright © 2023 Lahimer, Abou Diwan, Montjean, Cabry, Bach, Ajina, Ben Ali, Benkhalifa and Khorsi-Cauet. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Lahimer, Marwa Abou Diwan, Maria Montjean, Debbie Cabry, Rosalie Bach, Véronique Ajina, Mounir Ben Ali, Habib Benkhalifa, Moncef Khorsi-Cauet, Hafida Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
title | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
title_full | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
title_fullStr | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
title_full_unstemmed | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
title_short | Endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
title_sort | endocrine disrupting chemicals and male fertility: from physiological to molecular effects |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598475/ https://www.ncbi.nlm.nih.gov/pubmed/37886048 http://dx.doi.org/10.3389/fpubh.2023.1232646 |
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