Cargando…

Endocrine disrupting chemicals and male fertility: from physiological to molecular effects

The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogene...

Descripción completa

Detalles Bibliográficos
Autores principales: Lahimer, Marwa, Abou Diwan, Maria, Montjean, Debbie, Cabry, Rosalie, Bach, Véronique, Ajina, Mounir, Ben Ali, Habib, Benkhalifa, Moncef, Khorsi-Cauet, Hafida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598475/
https://www.ncbi.nlm.nih.gov/pubmed/37886048
http://dx.doi.org/10.3389/fpubh.2023.1232646
_version_ 1785125561637535744
author Lahimer, Marwa
Abou Diwan, Maria
Montjean, Debbie
Cabry, Rosalie
Bach, Véronique
Ajina, Mounir
Ben Ali, Habib
Benkhalifa, Moncef
Khorsi-Cauet, Hafida
author_facet Lahimer, Marwa
Abou Diwan, Maria
Montjean, Debbie
Cabry, Rosalie
Bach, Véronique
Ajina, Mounir
Ben Ali, Habib
Benkhalifa, Moncef
Khorsi-Cauet, Hafida
author_sort Lahimer, Marwa
collection PubMed
description The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogenesis, the maturation and competency of gametes and has guided scientists to hypothesize that endocrine disrupting chemicals (EDCs) may disrupt hormonal homoeostasis by leading to a wide range of hormonal control impairments. The effects of EDCs exposure on reproductive health are highly dependent on factors including the type of EDCs, the duration of exposure, individual susceptibility, and the presence of other co-factors. Research and scientists continue to study these complex interactions. The aim of this review is to summarize the literature to better understand the potential reproductive health risks of EDCs in France.
format Online
Article
Text
id pubmed-10598475
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-105984752023-10-26 Endocrine disrupting chemicals and male fertility: from physiological to molecular effects Lahimer, Marwa Abou Diwan, Maria Montjean, Debbie Cabry, Rosalie Bach, Véronique Ajina, Mounir Ben Ali, Habib Benkhalifa, Moncef Khorsi-Cauet, Hafida Front Public Health Public Health The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male fertility potential is well documented but still not fully elucidated. For example, the detection of industrial chemicals’ metabolites in seminal plasma and follicular fluid can affect efficiency of the gametogenesis, the maturation and competency of gametes and has guided scientists to hypothesize that endocrine disrupting chemicals (EDCs) may disrupt hormonal homoeostasis by leading to a wide range of hormonal control impairments. The effects of EDCs exposure on reproductive health are highly dependent on factors including the type of EDCs, the duration of exposure, individual susceptibility, and the presence of other co-factors. Research and scientists continue to study these complex interactions. The aim of this review is to summarize the literature to better understand the potential reproductive health risks of EDCs in France. Frontiers Media S.A. 2023-10-10 /pmc/articles/PMC10598475/ /pubmed/37886048 http://dx.doi.org/10.3389/fpubh.2023.1232646 Text en Copyright © 2023 Lahimer, Abou Diwan, Montjean, Cabry, Bach, Ajina, Ben Ali, Benkhalifa and Khorsi-Cauet. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Lahimer, Marwa
Abou Diwan, Maria
Montjean, Debbie
Cabry, Rosalie
Bach, Véronique
Ajina, Mounir
Ben Ali, Habib
Benkhalifa, Moncef
Khorsi-Cauet, Hafida
Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
title Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
title_full Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
title_fullStr Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
title_full_unstemmed Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
title_short Endocrine disrupting chemicals and male fertility: from physiological to molecular effects
title_sort endocrine disrupting chemicals and male fertility: from physiological to molecular effects
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598475/
https://www.ncbi.nlm.nih.gov/pubmed/37886048
http://dx.doi.org/10.3389/fpubh.2023.1232646
work_keys_str_mv AT lahimermarwa endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT aboudiwanmaria endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT montjeandebbie endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT cabryrosalie endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT bachveronique endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT ajinamounir endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT benalihabib endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT benkhalifamoncef endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects
AT khorsicauethafida endocrinedisruptingchemicalsandmalefertilityfromphysiologicaltomoleculareffects