Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor–modulating factors

In ischemic tissue, platelets can modulate angiogenesis. The specific factors influencing this function, however, are poorly understood. Here, we characterized the complement anaphylatoxin C5a-mediated activation of C5a receptor 1 (C5aR1) expressed on platelets as a potent regulator of ischemia-driv...

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Detalles Bibliográficos
Autores principales: Nording, Henry, Baron, Lasse, Sauter, Manuela, Lübken, Antje, Rawish, Elias, Szepanowski, Rebecca, von Esebeck, Jacob, Sun, Ying, Emami, Hossein, Meusel, Moritz, Saraei, Roza, Schanze, Nancy, Gorantla, Sivahari Prasad, von Bubnoff, Nikolas, Geisler, Tobias, von Hundelshausen, Philipp, Stellos, Konstantinos, Marquardt, Jens, Sadik, Christian D., Köhl, Jörg, Duerschmied, Daniel, Kleinschnitz, Christoph, Langer, Harald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598500/
https://www.ncbi.nlm.nih.gov/pubmed/37257194
http://dx.doi.org/10.1182/bloodadvances.2021006891

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