MAF functions as a pioneer transcription factor that initiates and sustains myelomagenesis

Deregulated expression of lineage-affiliated transcription factors (TFs) is a major mechanism of oncogenesis. However, how the deregulation of nonlineage affiliated TF affects chromatin to initiate oncogenic transcriptional programs is not well-known. To address this, we studied the chromatin effect...

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Detalles Bibliográficos
Autores principales: Katsarou, Alexia, Trasanidis, Nikolaos, Ponnusamy, Kanagaraju, Kostopoulos, Ioannis V., Alvarez-Benayas, Jaime, Papaleonidopoulou, Foteini, Keren, Keren, Sabbattini, Pierangela M. R., Feldhahn, Niklas, Papaioannou, Maria, Hatjiharissi, Evdoxia, Sudbery, Ian M., Chaidos, Aristeidis, Caputo, Valentina S., Karadimitris, Anastasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598502/
https://www.ncbi.nlm.nih.gov/pubmed/37224458
http://dx.doi.org/10.1182/bloodadvances.2023009772

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