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The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase

A considerable number of lytic polysaccharide monooxygenases (LPMOs) and other carbohydrate-active enzymes are modular, with catalytic domains being tethered to additional domains, such as carbohydrate-binding modules, by flexible linkers. While such linkers may affect the structure, function, and s...

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Detalles Bibliográficos
Autores principales: Forsberg, Zarah, Stepnov, Anton A., Tesei, Giulio, Wang, Yong, Buchinger, Edith, Kristiansen, Sandra K., Aachmann, Finn L., Arleth, Lise, Eijsink, Vincent G.H., Lindorff-Larsen, Kresten, Courtade, Gaston
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598543/
https://www.ncbi.nlm.nih.gov/pubmed/37734553
http://dx.doi.org/10.1016/j.jbc.2023.105262