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Analytical and clinical validation of a blood progranulin ELISA in frontotemporal dementias

OBJECTIVES: Heterozygous mutations in the granulin (GRN) gene may result in haploinsufficiency of progranulin (PGRN), which might lead to frontotemporal dementia (FTD). In this study, we aimed to perform analytical and clinical validation of a commercial progranulin kit for clinical use. METHODS: An...

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Detalles Bibliográficos
Autores principales:	Meda, Francisco, Simrén, Joel, Borroni, Barbara, Cantoni, Valentina, Archetti, Silvana, Biasiotto, Giorgio, Andreasson, Ulf, Blennow, Kaj, Kvartsberg, Hlin, Zetterberg, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598571/ https://www.ncbi.nlm.nih.gov/pubmed/37476993 http://dx.doi.org/10.1515/cclm-2023-0562

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