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Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach

[Image: see text] Due to their potential as leads for various therapeutic applications, including as antimitotic and antiparasitic agents, the development of tubulin inhibitors offers promise for drug discovery. In this study, an in silico pharmacophore-based virtual screening approach targeting the...

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Detalles Bibliográficos
Autores principales: Horgan, Mark James, Zell, Lukas, Siewert, Bianka, Stuppner, Hermann, Schuster, Daniela, Temml, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598795/
https://www.ncbi.nlm.nih.gov/pubmed/37774242
http://dx.doi.org/10.1021/acs.jcim.3c00939

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