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Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles

[Image: see text] Receptor-selective peptides are widely used as smart carriers for specific tumor-targeted delivery. A remarkable example is the cyclic nonapeptide iRGD (CRGDKPGDC, 1) that couples intrinsic cytotoxic effects with striking tumor-homing properties. These peculiar features are based o...

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Detalles Bibliográficos
Autores principales:	D’Amore, Vincenzo Maria, Donati, Greta, Lenci, Elena, Ludwig, Beatrice Stefanie, Kossatz, Susanne, Baiula, Monica, Trabocchi, Andrea, Kessler, Horst, Di Leva, Francesco Saverio, Marinelli, Luciana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598797/ https://www.ncbi.nlm.nih.gov/pubmed/37788340 http://dx.doi.org/10.1021/acs.jcim.3c01071

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