Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy

[Image: see text] Inducing paraptosis, a nonapoptotic form of cell death, has great therapeutic potential in cancer therapy, especially for drug-resistant tumors. However, the specific molecular target(s) that trigger paraptosis have not yet been deciphered yet. Herein, by using activity-based prote...

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Detalles Bibliográficos
Autores principales: Sun, Yong, Zheng, Hongbo, Qian, Lilin, Liu, Yue, Zhu, Deyu, Xu, Zejun, Chang, Wenqiang, Xu, Jianwei, Wang, Lei, Sun, Bin, Gu, Lichuan, Yuan, Huiqing, Lou, Hongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598831/
https://www.ncbi.nlm.nih.gov/pubmed/37885576
http://dx.doi.org/10.1021/jacsau.3c00228

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