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Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation

BACKGROUND: Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human models. However, their safety and durability as batten grafts for caudal septal deviation has not been documented. This study was designed to inv...

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Autores principales: Moon, Jee Won, Choi, Seok-Youl, Kim, Su-Jong, Shin, Jae-Min, Park, Il-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599004/
https://www.ncbi.nlm.nih.gov/pubmed/37876017
http://dx.doi.org/10.1186/s40463-023-00677-y
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author Moon, Jee Won
Choi, Seok-Youl
Kim, Su-Jong
Shin, Jae-Min
Park, Il-Ho
author_facet Moon, Jee Won
Choi, Seok-Youl
Kim, Su-Jong
Shin, Jae-Min
Park, Il-Ho
author_sort Moon, Jee Won
collection PubMed
description BACKGROUND: Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human models. However, their safety and durability as batten grafts for caudal septal deviation has not been documented. This study was designed to investigate the efficacy and safety of three-dimensional printed polycaprolactone mesh batten graft in septoplasty using the wedge resection technique for the correction of caudal septal deviation. METHODS: This retrospective study reviewed the medical records of 20 patients aged ≥ 18 years with caudal septal deviation who underwent septoplasty with wedge resection and three-dimensional printed polycaprolactone mesh graft from a tertiary medical center in South Korea, between December 1, 2019 and May 31, 2021. Those without nasal obstruction before surgery or with a short follow-up period (< 28 days) were excluded from the survey analysis. RESULTS: Of the 20 patients (mean age, 48.0 [range, 19–65] years), 17 (85.0%) were male, and three (15.0%) were female. A significant change was noted in the mean nasal obstruction symptom evaluation score (68.2 vs. 15.0, P < .001) in the 17 patients included in the analysis. Postoperative endoscopic evaluation revealed a straight septum in 19/20 (95.0%) patients, and no complications were noted in the postoperative follow-up period of up to 364 days. CONCLUSIONS: The three-dimensional printed polycaprolactone nasal mesh is safe and provides adequate support to resist the intrinsic memory of the cartilage of the caudal septum. In addition to nasal surgeries, it has great potential as a graft in other reconstructive surgeries. Trial registration Retrospectively registered.
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spelling pubmed-105990042023-10-26 Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation Moon, Jee Won Choi, Seok-Youl Kim, Su-Jong Shin, Jae-Min Park, Il-Ho J Otolaryngol Head Neck Surg Original Research Article BACKGROUND: Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human models. However, their safety and durability as batten grafts for caudal septal deviation has not been documented. This study was designed to investigate the efficacy and safety of three-dimensional printed polycaprolactone mesh batten graft in septoplasty using the wedge resection technique for the correction of caudal septal deviation. METHODS: This retrospective study reviewed the medical records of 20 patients aged ≥ 18 years with caudal septal deviation who underwent septoplasty with wedge resection and three-dimensional printed polycaprolactone mesh graft from a tertiary medical center in South Korea, between December 1, 2019 and May 31, 2021. Those without nasal obstruction before surgery or with a short follow-up period (< 28 days) were excluded from the survey analysis. RESULTS: Of the 20 patients (mean age, 48.0 [range, 19–65] years), 17 (85.0%) were male, and three (15.0%) were female. A significant change was noted in the mean nasal obstruction symptom evaluation score (68.2 vs. 15.0, P < .001) in the 17 patients included in the analysis. Postoperative endoscopic evaluation revealed a straight septum in 19/20 (95.0%) patients, and no complications were noted in the postoperative follow-up period of up to 364 days. CONCLUSIONS: The three-dimensional printed polycaprolactone nasal mesh is safe and provides adequate support to resist the intrinsic memory of the cartilage of the caudal septum. In addition to nasal surgeries, it has great potential as a graft in other reconstructive surgeries. Trial registration Retrospectively registered. BioMed Central 2023-10-24 /pmc/articles/PMC10599004/ /pubmed/37876017 http://dx.doi.org/10.1186/s40463-023-00677-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Original Research Article
Moon, Jee Won
Choi, Seok-Youl
Kim, Su-Jong
Shin, Jae-Min
Park, Il-Ho
Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
title Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
title_full Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
title_fullStr Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
title_full_unstemmed Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
title_short Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
title_sort wedge resection combined with 3d-printed polycaprolactone mesh for caudal septal deviation
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599004/
https://www.ncbi.nlm.nih.gov/pubmed/37876017
http://dx.doi.org/10.1186/s40463-023-00677-y
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