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JMJD6–BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells
BACKGROUND: Long non-coding RNA (lncRNA) HOTAIR acts importantly in liver cancer development, but its effect on radioresistance remains poorly understood. Here, our study probed into the possible impact of HOTAIR in radioresistance in liver cancer stem cells (LCSCs) and to elucidate its molecular ba...
Autores principales: | Pei, Ruifeng, Zhao, Le, Ding, Yiren, Su, Zhan, Li, Deqiang, Zhu, Shuo, Xu, Lu, Zhao, Wei, Zhou, Wuyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599021/ https://www.ncbi.nlm.nih.gov/pubmed/37880710 http://dx.doi.org/10.1186/s12967-023-04394-y |
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