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JMJD6–BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells

BACKGROUND: Long non-coding RNA (lncRNA) HOTAIR acts importantly in liver cancer development, but its effect on radioresistance remains poorly understood. Here, our study probed into the possible impact of HOTAIR in radioresistance in liver cancer stem cells (LCSCs) and to elucidate its molecular ba...

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Detalles Bibliográficos
Autores principales:	Pei, Ruifeng, Zhao, Le, Ding, Yiren, Su, Zhan, Li, Deqiang, Zhu, Shuo, Xu, Lu, Zhao, Wei, Zhou, Wuyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599021/ https://www.ncbi.nlm.nih.gov/pubmed/37880710 http://dx.doi.org/10.1186/s12967-023-04394-y

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