Basal Cell Carcinoma in the Periungual Region: A Rare Case and Pathogenesis Insights

This case report presents a rare occurrence of basal cell carcinoma (BCC) in the periungual region of the thumb. BCC is the most common type of skin cancer, typically found in sun-exposed areas. The discussion explores the underlying pathogenesis mechanisms, including the role of ultraviolet exposur...

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Detalles Bibliográficos
Autores principales: Martinez-Ortega, Jesus Ivan, Perez Hernandez, Felipe de Jesus, Reyes Garcia, Leslie Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599457/
https://www.ncbi.nlm.nih.gov/pubmed/37885494
http://dx.doi.org/10.7759/cureus.45934
Descripción
Sumario:This case report presents a rare occurrence of basal cell carcinoma (BCC) in the periungual region of the thumb. BCC is the most common type of skin cancer, typically found in sun-exposed areas. The discussion explores the underlying pathogenesis mechanisms, including the role of ultraviolet exposure, the absence of pilosebaceous units, and the involvement of the sonic hedgehog (SHH) pathway. Understanding the complexities of BCC in atypical locations is essential for effective prevention and treatment strategies.

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