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Abdominal surgery induces long-lasting changes in expression and binding of CTCF with impact on Major Histocompatibility Complex II transcription in circulating human monocytes

BACKGROUND: Postoperative immunosuppression has been recognized as an important driver of surgery-related morbidity and mortality. It is characterized by lymphocyte depression and impaired monocyte capability to present foreign antigens to T-cells via Major Histocompatibility Complex, Class II (MHC-...

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Detalles Bibliográficos
Autores principales:	Siegler, Benedikt Hermann, Thon, Jan Niklas, Altvater, Marc, Schenz, Judith, Larmann, Jan, Weigand, Markus Alexander, Weiterer, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599505/ https://www.ncbi.nlm.nih.gov/pubmed/37878653 http://dx.doi.org/10.1371/journal.pone.0293347

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