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Genes for highly abundant proteins in Escherichia coli avoid 5’ codons that promote ribosomal initiation
In many species highly expressed genes (HEGs) over-employ the synonymous codons that match the more abundant iso-acceptor tRNAs. Bacterial transgene codon randomization experiments report, however, that enrichment with such “translationally optimal” codons has little to no effect on the resultant pr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599525/ https://www.ncbi.nlm.nih.gov/pubmed/37878567 http://dx.doi.org/10.1371/journal.pcbi.1011581 |