Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study

The present study aims to determine the association between a genetic polymorphism of GSTP1 (rs1695) and the risk of periodontitis. This study used a cross-sectional design and included subjects from the South Indian population. A total of 100 individuals enrolled at Saveetha Dental College and Hosp...

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Autores principales: Saravanan, Rakshitha Vettri, Pandi, Anitha, Murthykumar, Karthikeyan, Selvi, Smiline Girija Aseervatham, Arumugam, Paramasivam, Jayaseelan, Vijayashree Priyadharsini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599595/
https://www.ncbi.nlm.nih.gov/pubmed/37886736
http://dx.doi.org/10.22099/mbrc.2023.46999.1815
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author Saravanan, Rakshitha Vettri
Pandi, Anitha
Murthykumar, Karthikeyan
Selvi, Smiline Girija Aseervatham
Arumugam, Paramasivam
Jayaseelan, Vijayashree Priyadharsini
author_facet Saravanan, Rakshitha Vettri
Pandi, Anitha
Murthykumar, Karthikeyan
Selvi, Smiline Girija Aseervatham
Arumugam, Paramasivam
Jayaseelan, Vijayashree Priyadharsini
author_sort Saravanan, Rakshitha Vettri
collection PubMed
description The present study aims to determine the association between a genetic polymorphism of GSTP1 (rs1695) and the risk of periodontitis. This study used a cross-sectional design and included subjects from the South Indian population. A total of 100 individuals enrolled at Saveetha Dental College and Hospital, Tamil Nadu were included in this study. The participants were divided into control (n=50) and periodontitis (n=50) based on clinical examination. Blood samples were collected. Genotyping was performed using specific primers spanning the polymorphic site. The genotypic frequencies for the rs1695 polymorphism were not significantly different between cases and controls.
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spelling pubmed-105995952023-10-26 Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study Saravanan, Rakshitha Vettri Pandi, Anitha Murthykumar, Karthikeyan Selvi, Smiline Girija Aseervatham Arumugam, Paramasivam Jayaseelan, Vijayashree Priyadharsini Mol Biol Res Commun Original Article The present study aims to determine the association between a genetic polymorphism of GSTP1 (rs1695) and the risk of periodontitis. This study used a cross-sectional design and included subjects from the South Indian population. A total of 100 individuals enrolled at Saveetha Dental College and Hospital, Tamil Nadu were included in this study. The participants were divided into control (n=50) and periodontitis (n=50) based on clinical examination. Blood samples were collected. Genotyping was performed using specific primers spanning the polymorphic site. The genotypic frequencies for the rs1695 polymorphism were not significantly different between cases and controls. Shiraz University 2023 /pmc/articles/PMC10599595/ /pubmed/37886736 http://dx.doi.org/10.22099/mbrc.2023.46999.1815 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Saravanan, Rakshitha Vettri
Pandi, Anitha
Murthykumar, Karthikeyan
Selvi, Smiline Girija Aseervatham
Arumugam, Paramasivam
Jayaseelan, Vijayashree Priyadharsini
Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study
title Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study
title_full Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study
title_fullStr Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study
title_full_unstemmed Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study
title_short Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study
title_sort genetic association between rs1695 in glutathione s-transferase p1 and risk of periodontitis: a pilot study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599595/
https://www.ncbi.nlm.nih.gov/pubmed/37886736
http://dx.doi.org/10.22099/mbrc.2023.46999.1815
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