Resolving a guanine-quadruplex structure in the SARS-CoV-2 genome through circular dichroism and multiscale molecular modeling

The genome of SARS-CoV-2 coronavirus is made up of a single-stranded RNA fragment that can assume a specific secondary structure, whose stability can influence the virus’s ability to reproduce. Recent studies have identified putative guanine quadruplex sequences in SARS-CoV-2 genome fragments that a...

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Detalles Bibliográficos
Autores principales: D'Anna, Luisa, Miclot, Tom, Bignon, Emmanuelle, Perricone, Ugo, Barone, Giampaolo, Monari, Antonio, Terenzi, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599604/
https://www.ncbi.nlm.nih.gov/pubmed/37886086
http://dx.doi.org/10.1039/d3sc04004f

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