Disrupting astrocyte-neuron lactate transport prevents cocaine seeking after prolonged withdrawal

Energy supply, especially the transfer of lactate from astrocytes to neurons, is critical for neuronal plasticity. However, its role in the incubation of cocaine craving remains largely unknown. Using an extended-access self-administration model and in vivo (1)H-magnetic resonance spectroscopy, we f...

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Detalles Bibliográficos
Autores principales: Chen, Wenjun, Zhang, Yan, Liang, Jie, Zhang, Zhongyu, Zhang, Libo, Huang, Enze, Zhang, Guipeng, Lu, Lin, Han, Ying, Shi, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599624/
https://www.ncbi.nlm.nih.gov/pubmed/37878699
http://dx.doi.org/10.1126/sciadv.adi4462

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