Cargando…

Analysis and experimental validation of fatty acid metabolism-related genes prostacyclin synthase (PTGIS) in endometrial cancer

The deregulation of fatty acid metabolism plays a pivotal role in cancer. Our objective is to construct a prognostic model for patients with endometrial carcinoma (EC) based on genes related to fatty acid metabolism-related genes (FAMGs). RNA sequencing and clinical data for EC were obtained from Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Bo, Ge, Shuwen, Wang, Zihao, Wang, Wantong, Wang, Yuting, Leng, Hongrui, Ma, Xiaoxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599728/ https://www.ncbi.nlm.nih.gov/pubmed/37796199 http://dx.doi.org/10.18632/aging.205080

Ejemplares similares

Affinity Isolation and Mass Spectrometry Identification of Prostacyclin Synthase (PTGIS) Subinteractome
por: Ershov, Pavel V., et al.
Publicado: (2019)

PTGIS May Be a Predictive Marker for Ovarian Cancer by Regulating Fatty Acid Metabolism
por: Wu, Xiaoqing, et al.
Publicado: (2023)

Validating the role of PTGIS gene in colorectal cancer by bioinformatics analysis and in vitro experiments
por: Ding, Hui, et al.
Publicado: (2023)

A novel predictive model based on inflammatory response-related genes for predicting endometrial cancer prognosis and its experimental validation
por: Wang, Yuting, et al.
Publicado: (2023)

Selective inhibition of prostacyclin synthase activity by rofecoxib
por: Griffoni, Cristiana, et al.
Publicado: (2007)

DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis
por: Pan, Xue-yin, et al.
Publicado: (2018)

Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16(−) NK-cell differentiation
por: Peng, Haiyan, et al.
Publicado: (2022)

Effects of Lipid Metabolism-Related Genes PTGIS and HRASLS on Phenotype, Prognosis, and Tumor Immunity in Lung Squamous Cell Carcinoma
por: Lei, Kai, et al.
Publicado: (2023)

Prostacyclin Synthesis and Prostacyclin Receptor Expression in the Porcine Myometrium: Prostacyclin Potential to Regulate Fatty Acid Transporters, Cytokines and Contractility-Related Factors
por: Blitek, Agnieszka, et al.
Publicado: (2022)

Alternative activation of macrophages by prostacyclin synthase ameliorates alcohol induced liver injury
por: Pan, Xue-yin, et al.
Publicado: (2021)

Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension
por: Wang, Xiao-Jian, et al.
Publicado: (2020)

Posttraumatic Growth and Its Measurement: A Closer Look at the PTGI’s Psychometric Properties and Structure
por: Jozefiaková, Bibiána, et al.
Publicado: (2022)

Common Multiple Primary Cancers Associated With Breast and Gynecologic Cancers and Their Risk Factors, Pathogenesis, Treatment and Prognosis: A Review
por: Ge, Shuwen, et al.
Publicado: (2022)

Nonsteroidal Anti-inflammatory Drug Interaction with Prostacyclin Synthase Protects from Miscarriage
por: Velez Edwards, Digna R., et al.
Publicado: (2017)

PROSTACYCLIN IN HEALTH AND DISEASE
Publicado: (1983)

Prostacyclin: An Inflammatory Paradox
por: Stitham, Jeremiah, et al.
Publicado: (2011)

The Prostacyclin Analog Beraprost Sodium Ameliorates Characteristics of Metabolic Syndrome in Obese Zucker (Fatty) Rats
por: Sato, Nahoko, et al.
Publicado: (2010)

ImmuneScore of eight-gene signature predicts prognosis and survival in patients with endometrial cancer
por: Gu, Jiahui, et al.
Publicado: (2023)

Involvement of DDAH/ADMA/NOS/cGMP and COX-2/PTGIS/cAMP Pathways in Human Tissue Kallikrein 1 Protecting Erectile Function in Aged Rats
por: Cui, Kai, et al.
Publicado: (2017)

Use of prostacyclin in pulmonary hypertension
por: Vicente, R, et al.
Publicado: (1998)

Role of prostacyclin in pulmonary hypertension
por: Mitchell, Jane A., et al.
Publicado: (2014)

Prostacyclin Regulation of Allergic Inflammation
por: Patel, Kunj, et al.
Publicado: (2022)

Hypoxia–Reoxygenation Triggers Coronary Vasospasm in Isolated Bovine Coronary Arteries via Tyrosine Nitration of Prostacyclin Synthase
por: Zou, Ming-Hui, et al.
Publicado: (1999)

Expression of Prostacyclin-Synthase in Human Breast Cancer: Negative Prognostic Factor and Protection against Cell Death In Vitro
por: Klein, Thomas, et al.
Publicado: (2015)

Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1
por: Sasaki, Yuka, et al.
Publicado: (2015)

Eicosanoids, prostacyclin and cyclooxygenase in the cardiovascular system
por: Mitchell, Jane A, et al.
Publicado: (2018)

Integrated bioinformatics analysis and experimental validation reveals fatty acid metabolism-related prognostic signature and immune responses for uterine corpus endometrial carcinoma
por: Guo, Chenrui, et al.
Publicado: (2022)

Prostacyclin Synthase: Upregulation during Renal Development and in Glomerular Disease as well as Its Constitutive Expression in Cultured Human Mesangial Cells
por: Klein, Thomas, et al.
Publicado: (2015)

Fatty acid synthase promotes breast cancer metastasis by mediating changes in fatty acid metabolism
por: Xu, Shuo, et al.
Publicado: (2021)

Prostacyclin and thromboxane in benign and malignant breast tumours.
por: Laekeman, G. M., et al.
Publicado: (1986)

The pulmonary and haematological toxicity of inhaled aerosolised prostacyclin
por: van Heerden, PV, et al.
Publicado: (1997)

“Yap”-ing about the Antifibrotic Benefits of Prostacyclin
por: Huang, Steven K.
Publicado: (2019)

Practical considerations for therapies targeting the prostacyclin pathway
por: Farber, Harrison W., et al.
Publicado: (2016)

Deep learning model for classifying endometrial lesions
por: Zhang, YunZheng, et al.
Publicado: (2021)

The role of prostacyclin in the interaction of endothelial cells and eosinophil granulocytes
por: Kónya, Viktória, et al.
Publicado: (2008)

Divergent roles of prostacyclin and PGE(2) in human tendinopathy
por: Bergqvist, Filip, et al.
Publicado: (2019)

Development and validation of a prognostic nomogram model incorporating routine laboratory biomarkers for preoperative patients with endometrial cancer
por: Cong, Rong, et al.
Publicado: (2023)

Prostacyclin Analogue Beraprost Inhibits Cardiac Fibroblast Proliferation Depending on Prostacyclin Receptor Activation through a TGF β-Smad Signal Pathway
por: Chen, Yun, et al.
Publicado: (2014)

Effect of Photo-Mediated Ultrasound Therapy on Nitric Oxide and Prostacyclin from Endothelial Cells
por: Karthikesh, Madhumithra Subramanian, et al.
Publicado: (2022)

Fatty Acid Synthase Is the Key Regulator of Fatty Acid Metabolism and Is Related to Immunotherapy in Bladder Cancer
por: Xiong, Qiao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2sfnoqtkllgskp4sksngkjs74j