An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury

Rivaroxaban is rarely associated with drug-induced liver injury (DILI). A 57-year-old male was sent to the emergency room from an endocrine clinic for a presyncope evaluation. His exam was non-focal, and his laboratory work was remarkable for the hepatocellular pattern of liver injury. Upon detailed...

Descripción completa

Detalles Bibliográficos
Autores principales: Karki, Bhesh R, Jasaraj, Ranjit B, Jha, Suman K, Maisuradze, Nodari, Yu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599792/
https://www.ncbi.nlm.nih.gov/pubmed/37885502
http://dx.doi.org/10.7759/cureus.45949
_version_ 1785125843554533376
author Karki, Bhesh R
Jasaraj, Ranjit B
Jha, Suman K
Maisuradze, Nodari
Yu, Qi
author_facet Karki, Bhesh R
Jasaraj, Ranjit B
Jha, Suman K
Maisuradze, Nodari
Yu, Qi
author_sort Karki, Bhesh R
collection PubMed
description Rivaroxaban is rarely associated with drug-induced liver injury (DILI). A 57-year-old male was sent to the emergency room from an endocrine clinic for a presyncope evaluation. His exam was non-focal, and his laboratory work was remarkable for the hepatocellular pattern of liver injury. Upon detailed assessment, he was found to have DILI due to rivaroxaban. The liver function tests improved after its discontinuation. This case emphasizes the need for early recognition and timely intervention to prevent further hepatotoxicity from the culprit drug.
format Online
Article
Text
id pubmed-10599792
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-105997922023-10-26 An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury Karki, Bhesh R Jasaraj, Ranjit B Jha, Suman K Maisuradze, Nodari Yu, Qi Cureus Gastroenterology Rivaroxaban is rarely associated with drug-induced liver injury (DILI). A 57-year-old male was sent to the emergency room from an endocrine clinic for a presyncope evaluation. His exam was non-focal, and his laboratory work was remarkable for the hepatocellular pattern of liver injury. Upon detailed assessment, he was found to have DILI due to rivaroxaban. The liver function tests improved after its discontinuation. This case emphasizes the need for early recognition and timely intervention to prevent further hepatotoxicity from the culprit drug. Cureus 2023-09-25 /pmc/articles/PMC10599792/ /pubmed/37885502 http://dx.doi.org/10.7759/cureus.45949 Text en Copyright © 2023, Karki et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Karki, Bhesh R
Jasaraj, Ranjit B
Jha, Suman K
Maisuradze, Nodari
Yu, Qi
An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury
title An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury
title_full An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury
title_fullStr An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury
title_full_unstemmed An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury
title_short An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury
title_sort uncommon side effect of rivaroxaban: a drug-induced liver injury
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10599792/
https://www.ncbi.nlm.nih.gov/pubmed/37885502
http://dx.doi.org/10.7759/cureus.45949
work_keys_str_mv AT karkibheshr anuncommonsideeffectofrivaroxabanadruginducedliverinjury
AT jasarajranjitb anuncommonsideeffectofrivaroxabanadruginducedliverinjury
AT jhasumank anuncommonsideeffectofrivaroxabanadruginducedliverinjury
AT maisuradzenodari anuncommonsideeffectofrivaroxabanadruginducedliverinjury
AT yuqi anuncommonsideeffectofrivaroxabanadruginducedliverinjury
AT karkibheshr uncommonsideeffectofrivaroxabanadruginducedliverinjury
AT jasarajranjitb uncommonsideeffectofrivaroxabanadruginducedliverinjury
AT jhasumank uncommonsideeffectofrivaroxabanadruginducedliverinjury
AT maisuradzenodari uncommonsideeffectofrivaroxabanadruginducedliverinjury
AT yuqi uncommonsideeffectofrivaroxabanadruginducedliverinjury

Ejemplares similares