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PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity

The conserved multiple PDZ-domain containing protein PATJ stabilizes the Crumbs-Pals1 complex to regulate apical-basal polarity and tight junction formation in epithelial cells. However, the molecular mechanism of PATJ’s function in these processes is still unclear. In this study, we demonstrate tha...

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Detalles Bibliográficos
Autores principales: Fiedler, Julia, Moennig, Thomas, Hinrichs, Johanna H., Weber, Annika, Wagner, Thomas, Hemmer, Tim, Schröter, Rita, Weide, Thomas, Epting, Daniel, Bergmann, Carsten, Nedvetsky, Pavel, Krahn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600057/
https://www.ncbi.nlm.nih.gov/pubmed/37878054
http://dx.doi.org/10.1007/s00018-023-04994-3