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PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity
The conserved multiple PDZ-domain containing protein PATJ stabilizes the Crumbs-Pals1 complex to regulate apical-basal polarity and tight junction formation in epithelial cells. However, the molecular mechanism of PATJ’s function in these processes is still unclear. In this study, we demonstrate tha...
Autores principales: | Fiedler, Julia, Moennig, Thomas, Hinrichs, Johanna H., Weber, Annika, Wagner, Thomas, Hemmer, Tim, Schröter, Rita, Weide, Thomas, Epting, Daniel, Bergmann, Carsten, Nedvetsky, Pavel, Krahn, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600057/ https://www.ncbi.nlm.nih.gov/pubmed/37878054 http://dx.doi.org/10.1007/s00018-023-04994-3 |
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