Cargando…

The lipolysis inhibitor acipimox reverses the cardiac phenotype induced by electronic cigarettes

Electronic cigarettes (e-cigarettes) are a prevalent alternative to conventional nicotine cigarettes among smokers and people who have never smoked. Increased concentrations of serum free fatty acids (FFAs) are crucial in generating lipotoxicity. We studied the effects of acipimox, an antilipolytic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Espinoza-Derout, Jorge, Arambulo, Jose Mari Luis, Ramirez-Trillo, William, Rivera, Juan Carlos, Hasan, Kamrul M., Lao, Candice J., Jordan, Maria C., Shao, Xuesi M., Roos, Kenneth P., Sinha-Hikim, Amiya P., Friedman, Theodore C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600141/ https://www.ncbi.nlm.nih.gov/pubmed/37880325 http://dx.doi.org/10.1038/s41598-023-44082-x

Ejemplares similares

LBSUN85 Acipimox Normalizes The Cardiac Phenotype Induced By Electronic Cigarettes
por: Espinoza-Derout, Jorge, et al.
Publicado: (2022)

Electronic Cigarette Use and the Risk of Cardiovascular Diseases
por: Espinoza-Derout, Jorge, et al.
Publicado: (2022)

SAT639 Electronic Cigarettes-exposed Mice Have Impairments In Skeletal Muscle Mediated By Impaired Ampk Activation
por: Rivera, Juan Carlos, et al.
Publicado: (2023)

SUN-603 Electronic Cigarette Exposure Induces Pro-Inflammatory Changes in Adipose Tissue in Apolipoprotein E (APOE) Knockout Mice
por: Espinoza-Derout, Jorge, et al.
Publicado: (2020)

Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis
por: Espinoza-Derout, Jorge, et al.
Publicado: (2019)

Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts
por: Hasan, Kamrul M., et al.
Publicado: (2020)

SUN-067 E-cigarettes and High Fat Diet Cause Alteration in Cardiac Structure and Function
por: Hasan, Kamrul, et al.
Publicado: (2019)

SUN-061 E-Cigarettes Alter Lipid Homeostasis and Cause Hepatic Steatosis in Diet-Induced Obesity
por: Hasan, Kamrul, et al.
Publicado: (2019)

MON-162 Hepatic DNA Damage Induced by ENDS Is Associated with Decreased Levels of NAD+
por: Espinoza-Derout, Jorge, et al.
Publicado: (2019)

Electronic cigarettes cause alteration in cardiac structure and function in diet-induced obese mice
por: Hasan, Kamrul M., et al.
Publicado: (2020)

RF32 | PSUN44 CARF Regulates Non-Alcoholic Fatty Liver Diseases (NAFLD) by Controlling ER Stress and Lipogenesis in Hepatic Cells.
por: Friedman, Theodore, et al.
Publicado: (2022)

ODP205 Hepatic steatosis induced by Nicotine plus Coca Cola is prevented by Nicotinamide riboside (NR) that increases mitochondrial NAD+
por: Friedman, Theodore C, et al.
Publicado: (2022)

CARF (CDKN2AIP) Regulates Hepatic Lipid Metabolism and Protects Against Development of Non-Alcoholic Fatty Liver Diseases
por: Hasan, Kamrul M, et al.
Publicado: (2021)

Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis
por: Hasan, Kamrul M., et al.
Publicado: (2023)

SUN-550 CARF Through Its Lipid Lowering Effect May Play a Pivotal Role in the Development of Non-Alcoholic Fatty Liver Diseases
por: Hasan, Kamrul M, et al.
Publicado: (2020)

Connection of Nicotine to Diet-Induced Obesity and Non-Alcoholic Fatty Liver Disease: Cellular and Mechanistic Insights
por: Sinha-Hikim, Amiya P., et al.
Publicado: (2017)

Acute reduction of lipolysis reduces adiponectin and IL-18: evidence from an intervention study with acipimox and insulin
por: Lindegaard, B., et al.
Publicado: (2013)

THU496 A Positive Relationship Exists Between CARF And AR In Prostate Cancer
por: Hasan, Kamrul M, et al.
Publicado: (2023)

RF19 | PSUN344 Control of Androgen Signaling and Metastasis by CARF in Prostate Cancer
por: Hasan, Kamrul, et al.
Publicado: (2022)

Acipimox inhibits human carbonic anhydrases
por: Mori, Mattia, et al.
Publicado: (2022)

Effect of Acipimox on Plasma Lipids and Glucose/Insulin in Pregnant Rats
por: Sánchez-Vera, I., et al.
Publicado: (2002)

Effects of phlorizin and acipimox on insulin resistance in STZ-diabetic rats.
por: Kim, Y. W., et al.
Publicado: (1995)

Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy
por: Abouhajar, Alaa, et al.
Publicado: (2022)

Correction: Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy
por: Abouhajar, Alaa, et al.
Publicado: (2022)

Editorial: Obesity, Smoking, and Fatty Liver Disease
por: Sinha-Hikim, Amiya P., et al.
Publicado: (2018)

Evidence for a Direct Effect of the NAD(+) Precursor Acipimox on Muscle Mitochondrial Function in Humans
por: van de Weijer, Tineke, et al.
Publicado: (2015)

Acipimox Administration With Exercise Induces a Co-feedback Action of the GH, PP, and PYY on Ghrelin Associated With a Reduction of Peripheral Lipolysis in Bulimic and Healthy-Weight Czech Women: A Randomized Study
por: Smitka, Kvido, et al.
Publicado: (2019)

Nicotine Synergizes with High-Fat Diet to Induce an Anti-Inflammatory Microenvironment to Promote Breast Tumor Growth
por: Jimenez, Thalia, et al.
Publicado: (2020)

Quantification of Acipimox in Plasma and Tissues by LC–MS/MS: Application to Pharmacokinetic Comparison between Normoxia and Hypoxia
por: Shen, Xin, et al.
Publicado: (2022)

Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome
por: Martinez, Jason E., et al.
Publicado: (2021)

The impact of short-term forearm immobilization and acipimox administration on muscle amino acid metabolism and insulin sensitivity in healthy, young volunteers
por: Dirks, Marlou L., et al.
Publicado: (2023)

RF32 | PSUN45 Nicotine E-Cigarette Vapors Exposure Disturbs 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in the Kidney May Contribute to E-Cigarette-Induced Blood Pressure Elevation in Mice
por: Liu, Jenny, et al.
Publicado: (2022)

Oncostatin M promotes lipolysis in white adipocytes
por: van Krieken, Pim P., et al.
Publicado: (2022)

THU476 Role Of Mitochondrial Sirtuins 3 And 5 On Glutamine Addiction In Prostate Cancer Cell
por: Hasan, Kamrul M, et al.
Publicado: (2023)

Role of β-Catenin in Post-Meiotic Male Germ Cell Differentiation
por: Chang, Yao-Fu, et al.
Publicado: (2011)

Nuclear Targeting of IGF-1 Receptor in Orbital Fibroblasts from Graves' Disease: Apparent Role of ADAM17
por: Hoa, Neil, et al.
Publicado: (2012)

Variation in lipolysis in milk from individual cows
por: Skipenes, P
Publicado: (1982)

Variation in lipolysis in milk from individual cows
por: Skipenes, P
Publicado: (1982)

Mathematical modeling of laser lipolysis
por: Mordon, Serge R, et al.
Publicado: (2008)

Treatment of Lipoma by Injection Lipolysis
por: Nanda, Soni
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_m1hij55p29tlq3hrfg28d7jdra