IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma

IDH1 mutations frequently occur early in human glioma. While IDH1 mutation has been shown to promote gliomagenesis via DNA and histone methylation, little is known regarding its regulation in antiviral immunity. Here, we discover that IDH1 mutation inhibits virus-induced interferon (IFN) antiviral r...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xueqin, Liu, Jun, Li, Yuqin, Zeng, Yuequan, Wang, Fang, Cheng, Zexiong, Duan, Hao, Pan, Guopeng, Yang, Shangqi, Chen, Yuling, Li, Qing, Shen, Xi, Li, Ying, Qin, Zixi, Chen, Jiahong, Huang, Youwei, Wang, Xiangyu, Lu, Yuli, Shu, Minfeng, Zhang, Yubo, Wang, Guocai, Li, Kai, Lin, Xi, Xing, Fan, Zhang, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600173/
https://www.ncbi.nlm.nih.gov/pubmed/37880243
http://dx.doi.org/10.1038/s41467-023-42545-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600173/
https://www.ncbi.nlm.nih.gov/pubmed/37880243
http://dx.doi.org/10.1038/s41467-023-42545-3

Ejemplares similares