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Cocaine-induced loss of LTD and social impairments are restored by fatty acid amide hydrolase inhibition

A single dose of cocaine abolishes endocannabinoid-mediated long-term depression (eCB-LTD) in the nucleus accumbens (NAc) within 24 h of administration. However, it is uncertain whether this altered neuroplasticity entails a behavioral deficit. As previously reported, after a single dose of cocaine...

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Detalles Bibliográficos
Autores principales: Alegre-Zurano, Laia, Caceres-Rodriguez, Alba, Berbegal-Sáez, Paula, Lassalle, Olivier, Manzoni, Olivier, Valverde, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600200/
https://www.ncbi.nlm.nih.gov/pubmed/37880305
http://dx.doi.org/10.1038/s41598-023-45476-7