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Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model

Caries and molar-incisor hypomineralization (MIH) are among the most prevalent diseases worldwide and need to be reliably diagnosed. The use of dental photographs and artificial intelligence (AI) methods may potentially contribute to realizing accurate and automated diagnostic visual examinations in...

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Autores principales: Felsch, Marco, Meyer, Ole, Schlickenrieder, Anne, Engels, Paula, Schönewolf, Jule, Zöllner, Felicitas, Heinrich-Weltzien, Roswitha, Hesenius, Marc, Hickel, Reinhard, Gruhn, Volker, Kühnisch, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600213/
https://www.ncbi.nlm.nih.gov/pubmed/37880375
http://dx.doi.org/10.1038/s41746-023-00944-2
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author Felsch, Marco
Meyer, Ole
Schlickenrieder, Anne
Engels, Paula
Schönewolf, Jule
Zöllner, Felicitas
Heinrich-Weltzien, Roswitha
Hesenius, Marc
Hickel, Reinhard
Gruhn, Volker
Kühnisch, Jan
author_facet Felsch, Marco
Meyer, Ole
Schlickenrieder, Anne
Engels, Paula
Schönewolf, Jule
Zöllner, Felicitas
Heinrich-Weltzien, Roswitha
Hesenius, Marc
Hickel, Reinhard
Gruhn, Volker
Kühnisch, Jan
author_sort Felsch, Marco
collection PubMed
description Caries and molar-incisor hypomineralization (MIH) are among the most prevalent diseases worldwide and need to be reliably diagnosed. The use of dental photographs and artificial intelligence (AI) methods may potentially contribute to realizing accurate and automated diagnostic visual examinations in the future. Therefore, the present study aimed to develop an AI-based algorithm that can detect, classify and localize caries and MIH. This study included an image set of 18,179 anonymous photographs. Pixelwise image labeling was achieved by trained and calibrated annotators using the Computer Vision Annotation Tool (CVAT). All annotations were made according to standard methods and were independently checked by an experienced dentist. The entire image set was divided into training (N = 16,679), validation (N = 500) and test sets (N = 1000). The AI-based algorithm was trained and finetuned over 250 epochs by using image augmentation and adapting a vision transformer network (SegFormer-B5). Statistics included the determination of the intersection over union (IoU), average precision (AP) and accuracy (ACC). The overall diagnostic performance in terms of IoU, AP and ACC were 0.959, 0.977 and 0.978 for the finetuned model, respectively. The corresponding data for the most relevant caries classes of non-cavitations (0.630, 0.813 and 0.990) and dentin cavities (0.692, 0.830, and 0.997) were found to be high. MIH-related demarcated opacity (0.672, 0.827, and 0.993) and atypical restoration (0.829, 0.902, and 0.999) showed similar results. Here, we report that the model achieves excellent precision for pixelwise detection and localization of caries and MIH. Nevertheless, the model needs to be further improved and externally validated.
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spelling pubmed-106002132023-10-27 Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model Felsch, Marco Meyer, Ole Schlickenrieder, Anne Engels, Paula Schönewolf, Jule Zöllner, Felicitas Heinrich-Weltzien, Roswitha Hesenius, Marc Hickel, Reinhard Gruhn, Volker Kühnisch, Jan NPJ Digit Med Article Caries and molar-incisor hypomineralization (MIH) are among the most prevalent diseases worldwide and need to be reliably diagnosed. The use of dental photographs and artificial intelligence (AI) methods may potentially contribute to realizing accurate and automated diagnostic visual examinations in the future. Therefore, the present study aimed to develop an AI-based algorithm that can detect, classify and localize caries and MIH. This study included an image set of 18,179 anonymous photographs. Pixelwise image labeling was achieved by trained and calibrated annotators using the Computer Vision Annotation Tool (CVAT). All annotations were made according to standard methods and were independently checked by an experienced dentist. The entire image set was divided into training (N = 16,679), validation (N = 500) and test sets (N = 1000). The AI-based algorithm was trained and finetuned over 250 epochs by using image augmentation and adapting a vision transformer network (SegFormer-B5). Statistics included the determination of the intersection over union (IoU), average precision (AP) and accuracy (ACC). The overall diagnostic performance in terms of IoU, AP and ACC were 0.959, 0.977 and 0.978 for the finetuned model, respectively. The corresponding data for the most relevant caries classes of non-cavitations (0.630, 0.813 and 0.990) and dentin cavities (0.692, 0.830, and 0.997) were found to be high. MIH-related demarcated opacity (0.672, 0.827, and 0.993) and atypical restoration (0.829, 0.902, and 0.999) showed similar results. Here, we report that the model achieves excellent precision for pixelwise detection and localization of caries and MIH. Nevertheless, the model needs to be further improved and externally validated. Nature Publishing Group UK 2023-10-25 /pmc/articles/PMC10600213/ /pubmed/37880375 http://dx.doi.org/10.1038/s41746-023-00944-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Felsch, Marco
Meyer, Ole
Schlickenrieder, Anne
Engels, Paula
Schönewolf, Jule
Zöllner, Felicitas
Heinrich-Weltzien, Roswitha
Hesenius, Marc
Hickel, Reinhard
Gruhn, Volker
Kühnisch, Jan
Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model
title Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model
title_full Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model
title_fullStr Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model
title_full_unstemmed Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model
title_short Detection and localization of caries and hypomineralization on dental photographs with a vision transformer model
title_sort detection and localization of caries and hypomineralization on dental photographs with a vision transformer model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600213/
https://www.ncbi.nlm.nih.gov/pubmed/37880375
http://dx.doi.org/10.1038/s41746-023-00944-2
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