Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants

With the rapid emergence of variants of concern (VOC), the efficacy of currently licensed vaccines has reduced drastically. VOC mutations largely occur in the S1 subunit of Spike. The S2 subunit of SARS-CoV-2 is conserved and thus more likely to elicit broadly reactive immune responses that could im...

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Detalles Bibliográficos
Autores principales: Mittal, Nidhi, Kumar, Sahil, Rajmani, Raju S., Singh, Randhir, Lemoine, Céline, Jakob, Virginie, BJ, Sowrabha, Jagannath, Nayana, Bhat, Madhuraj, Chakraborty, Debajyoti, Pandey, Suman, Jory, Aurélie, SA, Suba Soundarya, Kleanthous, Harry, Dubois, Patrice, Ringe, Rajesh P., Varadarajan, Raghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600342/
https://www.ncbi.nlm.nih.gov/pubmed/37880298
http://dx.doi.org/10.1038/s41541-023-00755-2

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