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Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis

OBJECTIVE: The aim of this study was to investigate the biomechanical stress of sandwich vertebrae (SVs) and common adjacent vertebrae in different degrees of spinal mobility in daily life. MATERIALS AND METHODS: A finite element model of the spinal segment of T10-L2 was developed and validated. Sim...

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Autores principales: Huang, Shaolong, Zhou, Chengqiang, Zhang, Xu, Tang, Zhongjian, Liu, Liangyu, Meng, Xiao, Xue, Cheng, Tang, Xianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600377/
https://www.ncbi.nlm.nih.gov/pubmed/37900139
http://dx.doi.org/10.3389/fendo.2023.1259095
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author Huang, Shaolong
Zhou, Chengqiang
Zhang, Xu
Tang, Zhongjian
Liu, Liangyu
Meng, Xiao
Xue, Cheng
Tang, Xianye
author_facet Huang, Shaolong
Zhou, Chengqiang
Zhang, Xu
Tang, Zhongjian
Liu, Liangyu
Meng, Xiao
Xue, Cheng
Tang, Xianye
author_sort Huang, Shaolong
collection PubMed
description OBJECTIVE: The aim of this study was to investigate the biomechanical stress of sandwich vertebrae (SVs) and common adjacent vertebrae in different degrees of spinal mobility in daily life. MATERIALS AND METHODS: A finite element model of the spinal segment of T10-L2 was developed and validated. Simultaneously, T11 and L1 fractures were simulated, and a 6-ml bone cement was constructed in their center. Under the condition of applying a 500-N axial load to the upper surface of T10 and immobilizing the lower surface of L2, moments were applied to the upper surface of T10, T11, T12, L1, and L2 and divided into five groups: M-T10, M-T11, M-T12, M-L1, and M-L2. The maximum von Mises stress of T10, T12, and L2 in different groups was calculated and analyzed. RESULTS: The maximum von Mises stress of T10 in the M-T10 group was 30.68 MPa, 36.13 MPa, 34.27 MPa, 33.43 MPa, 26.86 MPa, and 27.70 MPa greater than the maximum stress value of T10 in the other groups in six directions of load flexion, extension, left and right lateral bending, and left and right rotation, respectively. The T12 stress value in the M-T12 group was 29.62 MPa, 32.63 MPa, 30.03 MPa, 31.25 MPa, 26.38 MPa, and 26.25 MPa greater than the T12 stress value in the other groups in six directions. The maximum stress of L2 in M-T12 in the M-L2 group was 25.48 MPa, 36.38 MPa, 31.99 MPa, 31.07 MPa, 30.36 MPa, and 32.07 MPa, which was greater than the stress value of L2 in the other groups. When the load is on which vertebral body, it is subjected to the greatest stress. CONCLUSION: We found that SVs did not always experience the highest stress. The most stressed vertebrae vary with the degree of curvature of the spine. Patients should be encouraged to avoid the same spinal curvature posture for a long time in life and work or to wear a spinal brace for protection after surgery, which can avoid long-term overload on a specific spine and disrupt its blood supply, resulting in more severe loss of spinal quality and increasing the possibility of fractures.
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spelling pubmed-106003772023-10-27 Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis Huang, Shaolong Zhou, Chengqiang Zhang, Xu Tang, Zhongjian Liu, Liangyu Meng, Xiao Xue, Cheng Tang, Xianye Front Endocrinol (Lausanne) Endocrinology OBJECTIVE: The aim of this study was to investigate the biomechanical stress of sandwich vertebrae (SVs) and common adjacent vertebrae in different degrees of spinal mobility in daily life. MATERIALS AND METHODS: A finite element model of the spinal segment of T10-L2 was developed and validated. Simultaneously, T11 and L1 fractures were simulated, and a 6-ml bone cement was constructed in their center. Under the condition of applying a 500-N axial load to the upper surface of T10 and immobilizing the lower surface of L2, moments were applied to the upper surface of T10, T11, T12, L1, and L2 and divided into five groups: M-T10, M-T11, M-T12, M-L1, and M-L2. The maximum von Mises stress of T10, T12, and L2 in different groups was calculated and analyzed. RESULTS: The maximum von Mises stress of T10 in the M-T10 group was 30.68 MPa, 36.13 MPa, 34.27 MPa, 33.43 MPa, 26.86 MPa, and 27.70 MPa greater than the maximum stress value of T10 in the other groups in six directions of load flexion, extension, left and right lateral bending, and left and right rotation, respectively. The T12 stress value in the M-T12 group was 29.62 MPa, 32.63 MPa, 30.03 MPa, 31.25 MPa, 26.38 MPa, and 26.25 MPa greater than the T12 stress value in the other groups in six directions. The maximum stress of L2 in M-T12 in the M-L2 group was 25.48 MPa, 36.38 MPa, 31.99 MPa, 31.07 MPa, 30.36 MPa, and 32.07 MPa, which was greater than the stress value of L2 in the other groups. When the load is on which vertebral body, it is subjected to the greatest stress. CONCLUSION: We found that SVs did not always experience the highest stress. The most stressed vertebrae vary with the degree of curvature of the spine. Patients should be encouraged to avoid the same spinal curvature posture for a long time in life and work or to wear a spinal brace for protection after surgery, which can avoid long-term overload on a specific spine and disrupt its blood supply, resulting in more severe loss of spinal quality and increasing the possibility of fractures. Frontiers Media S.A. 2023-10-11 /pmc/articles/PMC10600377/ /pubmed/37900139 http://dx.doi.org/10.3389/fendo.2023.1259095 Text en Copyright © 2023 Huang, Zhou, Zhang, Tang, Liu, Meng, Xue and Tang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Huang, Shaolong
Zhou, Chengqiang
Zhang, Xu
Tang, Zhongjian
Liu, Liangyu
Meng, Xiao
Xue, Cheng
Tang, Xianye
Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis
title Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis
title_full Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis
title_fullStr Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis
title_full_unstemmed Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis
title_short Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis
title_sort biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600377/
https://www.ncbi.nlm.nih.gov/pubmed/37900139
http://dx.doi.org/10.3389/fendo.2023.1259095
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