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Evaluation of the efficacy of mitochondrial fission inhibitor (Mdivi-1) using non-alcoholic steatohepatitis (NASH) liver organoids

Non-alcoholic steatohepatitis (NASH) is known to progress to cirrhosis and hepatocellular carcinoma in some patients. Although NASH is associated with abnormal mitochondrial function related to lipid metabolism, mechanisms for the development and effective treatments are still unclear. Therefore, ne...

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Detalles Bibliográficos
Autores principales: Elbadawy, Mohamed, Tanabe, Kiwamu, Yamamoto, Haru, Ishihara, Yusuke, Mochizuki, Maria, Abugomaa, Amira, Yamawaki, Hideyuki, Kaneda, Masahiro, Usui, Tatsuya, Sasaki, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600465/
https://www.ncbi.nlm.nih.gov/pubmed/37900170
http://dx.doi.org/10.3389/fphar.2023.1243258

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