Successful management of nasopharyngitis caused by Schizophyllum commune in a captive cheetah (Acinonyx jubatus)

Herein, we describe the management of nasopharyngitis caused by Schizophyllum commune infection in a captive cheetah. Computed tomography revealed a nodule in the nasal cavity and pharynx, and an endoscopic biopsy was performed. As a result, the nodule was surgically resected because of a suspected...

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Detalles Bibliográficos
Autores principales: NOGUCHI, Shunsuke, TOYOTA, Kosuke, OZAKI, Miki, WADA, Yusuke, TAKAMI, Yuki, TANAKA, Miyuu, KUWAMURA, Mitsuru, SHIMADA, Terumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2023
Materias:
Wildlife Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600532/
https://www.ncbi.nlm.nih.gov/pubmed/37574282
http://dx.doi.org/10.1292/jvms.23-0273
Descripción
Sumario:Herein, we describe the management of nasopharyngitis caused by Schizophyllum commune infection in a captive cheetah. Computed tomography revealed a nodule in the nasal cavity and pharynx, and an endoscopic biopsy was performed. As a result, the nodule was surgically resected because of a suspected carcinoma. However, the surgical specimen was histologically re-evaluated and a fungal granuloma was diagnosed. Sequence analysis of DNA from formalin-fixed, paraffin-embedded samples revealed S. commune infection. The cheetah was administered fluconazole orally for 73 days. However, the drug was ineffective and itraconazole was administered for 14 days. Symptoms such as nasal discharge and sneezing have completely resolved for 4 years.

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