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Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia
Lung infiltrates are frequently observed in patients with COVID-19 infection and require specialized management. Identifying reliable laboratory parameters to reduce the need for chest CT scans in non-desaturation patients is of great interest. This study aimed to investigate the potential of C-reac...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600661/ https://www.ncbi.nlm.nih.gov/pubmed/37900075 http://dx.doi.org/10.25122/jml-2023-0104 |
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author | Atef, Moaz Eid, Hoda Amin, Mohammad Shehata, Mohamad Shaarawy, Ahmed Nabawy, Osama Wahba, Ahmed Aboseif, Ahmed Rakha, Mohamed Zaki, Mohamed Mohammed, Eid Albalsha, Abdullah Nour, Sameh Rezk, Amr Shaheen, Mohamed Kabil, Ahmed |
author_facet | Atef, Moaz Eid, Hoda Amin, Mohammad Shehata, Mohamad Shaarawy, Ahmed Nabawy, Osama Wahba, Ahmed Aboseif, Ahmed Rakha, Mohamed Zaki, Mohamed Mohammed, Eid Albalsha, Abdullah Nour, Sameh Rezk, Amr Shaheen, Mohamed Kabil, Ahmed |
author_sort | Atef, Moaz |
collection | PubMed |
description | Lung infiltrates are frequently observed in patients with COVID-19 infection and require specialized management. Identifying reliable laboratory parameters to reduce the need for chest CT scans in non-desaturation patients is of great interest. This study aimed to investigate the potential of C-reactive protein (CRP) as an indicator to identify the presence of lung infiltrates in early COVID-19 infection. The study was conducted at Al-Azhar University hospitals from May 2021 to March 2022 and included 210 patients with COVID-19 infection confirmed by positive PCR, all of whom were previously healthy, non-smokers, and non-hypoxemic. CRP levels were assessed and correlated with lung infiltrates observed in CT chest examinations. The mean value of CRP was 40.3±14.3 mg/L in males and 36.6±15.2 mg/L among females. One hundred sixty-two patients had pneumonic infiltrates, while 48 had no infiltrates. The mean value of CRP was 45.02±10.2 mg/L in patients with radiological infiltrates and 18.8±7.8 mg/L in patients without radiological infiltrates. Based on our findings, a CRP value greater than 29.8 mg/L was suggested as a cut-off value to indicate the presence of lung infiltrates. CRP is a simple laboratory marker that, at certain limits, may point to the presence of pneumonic infiltrates in early non-hypoxemic patients with COVID-19 infection. |
format | Online Article Text |
id | pubmed-10600661 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-106006612023-10-27 Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia Atef, Moaz Eid, Hoda Amin, Mohammad Shehata, Mohamad Shaarawy, Ahmed Nabawy, Osama Wahba, Ahmed Aboseif, Ahmed Rakha, Mohamed Zaki, Mohamed Mohammed, Eid Albalsha, Abdullah Nour, Sameh Rezk, Amr Shaheen, Mohamed Kabil, Ahmed J Med Life Original Article Lung infiltrates are frequently observed in patients with COVID-19 infection and require specialized management. Identifying reliable laboratory parameters to reduce the need for chest CT scans in non-desaturation patients is of great interest. This study aimed to investigate the potential of C-reactive protein (CRP) as an indicator to identify the presence of lung infiltrates in early COVID-19 infection. The study was conducted at Al-Azhar University hospitals from May 2021 to March 2022 and included 210 patients with COVID-19 infection confirmed by positive PCR, all of whom were previously healthy, non-smokers, and non-hypoxemic. CRP levels were assessed and correlated with lung infiltrates observed in CT chest examinations. The mean value of CRP was 40.3±14.3 mg/L in males and 36.6±15.2 mg/L among females. One hundred sixty-two patients had pneumonic infiltrates, while 48 had no infiltrates. The mean value of CRP was 45.02±10.2 mg/L in patients with radiological infiltrates and 18.8±7.8 mg/L in patients without radiological infiltrates. Based on our findings, a CRP value greater than 29.8 mg/L was suggested as a cut-off value to indicate the presence of lung infiltrates. CRP is a simple laboratory marker that, at certain limits, may point to the presence of pneumonic infiltrates in early non-hypoxemic patients with COVID-19 infection. Carol Davila University Press 2023-07 /pmc/articles/PMC10600661/ /pubmed/37900075 http://dx.doi.org/10.25122/jml-2023-0104 Text en ©2023 JOURNAL of MEDICINE and LIFE https://creativecommons.org/licenses/by/3.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Original Article Atef, Moaz Eid, Hoda Amin, Mohammad Shehata, Mohamad Shaarawy, Ahmed Nabawy, Osama Wahba, Ahmed Aboseif, Ahmed Rakha, Mohamed Zaki, Mohamed Mohammed, Eid Albalsha, Abdullah Nour, Sameh Rezk, Amr Shaheen, Mohamed Kabil, Ahmed Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia |
title | Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia |
title_full | Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia |
title_fullStr | Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia |
title_full_unstemmed | Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia |
title_short | Assessment of C-reactive protein levels as an indicator for lung infiltrates in patients with COVID-19 pneumonia |
title_sort | assessment of c-reactive protein levels as an indicator for lung infiltrates in patients with covid-19 pneumonia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600661/ https://www.ncbi.nlm.nih.gov/pubmed/37900075 http://dx.doi.org/10.25122/jml-2023-0104 |
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