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Testicular mixed germ cell tumor: A case report

BACKGROUND: Testicular mixed germ cell tumors (TMGCTs) are rare malignant tumors that are more common in men aged 20–40 years. TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis. Their onset is undetectable; thus, early diagnosis is challenging. However, early rec...

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Detalles Bibliográficos
Autores principales: Xiao, Qi-Fan, Li, Jie, Tang, Bin, Zhu, Yu-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600853/
https://www.ncbi.nlm.nih.gov/pubmed/37901019
http://dx.doi.org/10.12998/wjcc.v11.i28.6902
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author Xiao, Qi-Fan
Li, Jie
Tang, Bin
Zhu, Yu-Qing
author_facet Xiao, Qi-Fan
Li, Jie
Tang, Bin
Zhu, Yu-Qing
author_sort Xiao, Qi-Fan
collection PubMed
description BACKGROUND: Testicular mixed germ cell tumors (TMGCTs) are rare malignant tumors that are more common in men aged 20–40 years. TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis. Their onset is undetectable; thus, early diagnosis is challenging. However, early recognition and diagnosis substantially improve patient prognosis. CASE SUMMARY: We evaluated a rare case of TMGCT in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis instead of testicular enlargement and pain, which may easily lead to misdiagnosis. We report the clinical signs and symptoms, histopathological characteristics, and immunohistochemical results of this case of malignant TMGCT. CONCLUSION: Our case, which was typical with multiple components, along with a literature review, may serve as a basis for early diagnosis.
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spelling pubmed-106008532023-10-27 Testicular mixed germ cell tumor: A case report Xiao, Qi-Fan Li, Jie Tang, Bin Zhu, Yu-Qing World J Clin Cases Case Report BACKGROUND: Testicular mixed germ cell tumors (TMGCTs) are rare malignant tumors that are more common in men aged 20–40 years. TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis. Their onset is undetectable; thus, early diagnosis is challenging. However, early recognition and diagnosis substantially improve patient prognosis. CASE SUMMARY: We evaluated a rare case of TMGCT in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis instead of testicular enlargement and pain, which may easily lead to misdiagnosis. We report the clinical signs and symptoms, histopathological characteristics, and immunohistochemical results of this case of malignant TMGCT. CONCLUSION: Our case, which was typical with multiple components, along with a literature review, may serve as a basis for early diagnosis. Baishideng Publishing Group Inc 2023-10-06 2023-10-06 /pmc/articles/PMC10600853/ /pubmed/37901019 http://dx.doi.org/10.12998/wjcc.v11.i28.6902 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Xiao, Qi-Fan
Li, Jie
Tang, Bin
Zhu, Yu-Qing
Testicular mixed germ cell tumor: A case report
title Testicular mixed germ cell tumor: A case report
title_full Testicular mixed germ cell tumor: A case report
title_fullStr Testicular mixed germ cell tumor: A case report
title_full_unstemmed Testicular mixed germ cell tumor: A case report
title_short Testicular mixed germ cell tumor: A case report
title_sort testicular mixed germ cell tumor: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10600853/
https://www.ncbi.nlm.nih.gov/pubmed/37901019
http://dx.doi.org/10.12998/wjcc.v11.i28.6902
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