Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations

BACKGROUND: Tuberous sclerosis complex (TSC) is an inherited neurocutaneous disorder caused by mutations in the TSC1 or TSC2 genes, with patients often exhibiting neurodevelopmental (ND) manifestations termed TSC-associated neuropsychiatric disorders (TAND) including autism spectrum disorder (ASD) a...

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Detalles Bibliográficos
Autores principales: Aksoylu, Inci S., Martin, Pauline, Robert, Francis, Szkop, Krzysztof J., Redmond, Nicholas E., Bhattacharyya, Srirupa, Wang, Jennifer, Chen, Shan, Beauchamp, Roberta L., Nobeli, Irene, Pelletier, Jerry, Larsson, Ola, Ramesh, Vijaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601155/
https://www.ncbi.nlm.nih.gov/pubmed/37880800
http://dx.doi.org/10.1186/s13229-023-00572-3

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