ACSL4 inhibition prevents macrophage ferroptosis and alleviates fibrosis in bleomycin-induced systemic sclerosis model

BACKGROUND: Systemic sclerosis (SSc), with unclear pathophysiology, is a paradigmatic rheumatic disease of immunity dysfunction-driven multi-organ inflammation and ultimate fibrosis. Pathogenesis breakthroughs are urgently needed for available treatments halting its unremitting stiffness. This study...

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Detalles Bibliográficos
Autores principales: Cao, Dianyu, Zheng, Jina, Li, Zheng, Yu, Yong, Chen, Zengrui, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601156/
https://www.ncbi.nlm.nih.gov/pubmed/37884942
http://dx.doi.org/10.1186/s13075-023-03190-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601156/
https://www.ncbi.nlm.nih.gov/pubmed/37884942
http://dx.doi.org/10.1186/s13075-023-03190-9

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