Fasting mimicking diet inhibits tumor-associated macrophage survival and pro-tumor function in hypoxia: implications for combination therapy with anti-angiogenic agent

BACKGROUND: Recent research shows that tumor-associated macrophages (TAMs) are the primary consumers of glucose in tumor tissue, surpassing that of tumor cells. Our previous studies revealed that inhibiting glucose uptake impairs the survival and tumor-promoting function of hypoxic TAMs, suggesting...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Wang, Yu-jie, Wang, Rong, Gong, Fu-lian, Shi, Yu-huan, Li, Sheng-nan, Chen, Pan-pan, Yuan, Yong-fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601181/
https://www.ncbi.nlm.nih.gov/pubmed/37884960
http://dx.doi.org/10.1186/s12967-023-04577-7

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