Silencing of CD147 inhibits cell proliferation, migration, invasion, lipid metabolism dysregulation and promotes apoptosis in lung adenocarcinoma via blocking the Rap1 signaling pathway

OBJECTIVE: CD147 is an important glycoprotein that participates in the progression of diverse cancers. This study aims to explore the specific function of CD147 in lung adenocarcinoma (LUAD) and to reveal related downstream molecular mechanisms. METHODS: Followed by silencing of CD147, the viability...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Liu, Zhouzhong, Lai, Xuwang, Liu, Shubin, Wang, Yuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601207/
https://www.ncbi.nlm.nih.gov/pubmed/37880644
http://dx.doi.org/10.1186/s12931-023-02532-0

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