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The Quartet Data Portal: integration of community-wide resources for multiomics quality control

The Quartet Data Portal facilitates community access to well-characterized reference materials, reference datasets, and related resources established based on a family of four individuals with identical twins from the Quartet Project. Users can request DNA, RNA, protein, and metabolite reference mat...

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Detalles Bibliográficos
Autores principales: Yang, Jingcheng, Liu, Yaqing, Shang, Jun, Chen, Qiaochu, Chen, Qingwang, Ren, Luyao, Zhang, Naixin, Yu, Ying, Li, Zhihui, Song, Yueqiang, Yang, Shengpeng, Scherer, Andreas, Tong, Weida, Hong, Huixiao, Xiao, Wenming, Shi, Leming, Zheng, Yuanting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601216/
https://www.ncbi.nlm.nih.gov/pubmed/37884999
http://dx.doi.org/10.1186/s13059-023-03091-9
Descripción
Sumario:The Quartet Data Portal facilitates community access to well-characterized reference materials, reference datasets, and related resources established based on a family of four individuals with identical twins from the Quartet Project. Users can request DNA, RNA, protein, and metabolite reference materials, as well as datasets generated across omics, platforms, labs, protocols, and batches. Reproducible analysis tools allow for objective performance assessment of user-submitted data, while interactive visualization tools support rapid exploration of reference datasets. A closed-loop “distribution-collection-evaluation-integration” workflow enables updates and integration of community-contributed multiomics data. Ultimately, this portal helps promote the advancement of reference datasets and multiomics quality control. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13059-023-03091-9.