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Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study

INTRODUCTION: Unintentional dural puncture (UDP) occurs in 0.5–1.5% of labour epidural analgesia cases. To date, little is known about evidence of UDP-related complications. This work aimed to assess the incidence of intrapartum and postpartum complications in parturients who experienced UDP. METHOD...

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Autores principales: Poma, S., Bonomo, M. C., Gazzaniga, G., Pizzulli, M., De Silvestri, A., Baldi, C., Broglia, F., Ciceri, M., Fuardo, M., Morgante, F., Pellicori, S., Roldi, E. M., Delmonte, M. P., Mojoli, F., Locatelli, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601237/
https://www.ncbi.nlm.nih.gov/pubmed/37880725
http://dx.doi.org/10.1186/s44158-023-00127-1
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author Poma, S.
Bonomo, M. C.
Gazzaniga, G.
Pizzulli, M.
De Silvestri, A.
Baldi, C.
Broglia, F.
Ciceri, M.
Fuardo, M.
Morgante, F.
Pellicori, S.
Roldi, E. M.
Delmonte, M. P.
Mojoli, F.
Locatelli, A.
author_facet Poma, S.
Bonomo, M. C.
Gazzaniga, G.
Pizzulli, M.
De Silvestri, A.
Baldi, C.
Broglia, F.
Ciceri, M.
Fuardo, M.
Morgante, F.
Pellicori, S.
Roldi, E. M.
Delmonte, M. P.
Mojoli, F.
Locatelli, A.
author_sort Poma, S.
collection PubMed
description INTRODUCTION: Unintentional dural puncture (UDP) occurs in 0.5–1.5% of labour epidural analgesia cases. To date, little is known about evidence of UDP-related complications. This work aimed to assess the incidence of intrapartum and postpartum complications in parturients who experienced UDP. METHODS: This is a 10-year retrospective observational study on parturients admitted to our centre who presented UDP. Data collection gathered UDP-related complications during labour and postpartum. All women who displayed UDP received medical therapy and bed rest. An epidural blood patch (EBP) was not used in this population. Once asymptomatic, patients were discharged from the hospital. RESULTS: Out of 7718 neuraxial analgesia cases, 97 cases of UDP occurred (1.25%). During labour, complications appeared in a small percentage of analgesia procedures performed, including total spinal anaesthesia (1.0%), extended motor block (3%), hypotension (4.1%), abnormal foetal heart rate (2%), inadequate analgesia (14.4%), and general anaesthesia following neuraxial anaesthesia failure (33.3% of emergency caesarean sections). During the postpartum period, 53.6% of parturients exhibited a postdural puncture headache, 13.4% showed neurological symptoms, and 14.4% required neurological consultation and neuroimaging. No patient developed subdural hematoma or cerebral venous sinus thrombosis; one woman presented posterior reversible encephalopathy syndrome associated with eclampsia. Overall, 82.5% of women experienced an extension of hospital stay. CONCLUSION: Major complications occurred in a small percentage of patients during labour. However, since they represent high-risk maternal and neonatal health events, a dedicated anaesthesiologist and a trained obstetric team are essential. No major neurological complications were registered postpartum, and EBP was not performed. Nevertheless, all patients with UDP were carefully monitored and treated until complete recovery before discharge, leading to an extension of their hospitalization.
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spelling pubmed-106012372023-10-27 Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study Poma, S. Bonomo, M. C. Gazzaniga, G. Pizzulli, M. De Silvestri, A. Baldi, C. Broglia, F. Ciceri, M. Fuardo, M. Morgante, F. Pellicori, S. Roldi, E. M. Delmonte, M. P. Mojoli, F. Locatelli, A. J Anesth Analg Crit Care Original Article INTRODUCTION: Unintentional dural puncture (UDP) occurs in 0.5–1.5% of labour epidural analgesia cases. To date, little is known about evidence of UDP-related complications. This work aimed to assess the incidence of intrapartum and postpartum complications in parturients who experienced UDP. METHODS: This is a 10-year retrospective observational study on parturients admitted to our centre who presented UDP. Data collection gathered UDP-related complications during labour and postpartum. All women who displayed UDP received medical therapy and bed rest. An epidural blood patch (EBP) was not used in this population. Once asymptomatic, patients were discharged from the hospital. RESULTS: Out of 7718 neuraxial analgesia cases, 97 cases of UDP occurred (1.25%). During labour, complications appeared in a small percentage of analgesia procedures performed, including total spinal anaesthesia (1.0%), extended motor block (3%), hypotension (4.1%), abnormal foetal heart rate (2%), inadequate analgesia (14.4%), and general anaesthesia following neuraxial anaesthesia failure (33.3% of emergency caesarean sections). During the postpartum period, 53.6% of parturients exhibited a postdural puncture headache, 13.4% showed neurological symptoms, and 14.4% required neurological consultation and neuroimaging. No patient developed subdural hematoma or cerebral venous sinus thrombosis; one woman presented posterior reversible encephalopathy syndrome associated with eclampsia. Overall, 82.5% of women experienced an extension of hospital stay. CONCLUSION: Major complications occurred in a small percentage of patients during labour. However, since they represent high-risk maternal and neonatal health events, a dedicated anaesthesiologist and a trained obstetric team are essential. No major neurological complications were registered postpartum, and EBP was not performed. Nevertheless, all patients with UDP were carefully monitored and treated until complete recovery before discharge, leading to an extension of their hospitalization. BioMed Central 2023-10-25 /pmc/articles/PMC10601237/ /pubmed/37880725 http://dx.doi.org/10.1186/s44158-023-00127-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Poma, S.
Bonomo, M. C.
Gazzaniga, G.
Pizzulli, M.
De Silvestri, A.
Baldi, C.
Broglia, F.
Ciceri, M.
Fuardo, M.
Morgante, F.
Pellicori, S.
Roldi, E. M.
Delmonte, M. P.
Mojoli, F.
Locatelli, A.
Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study
title Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study
title_full Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study
title_fullStr Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study
title_full_unstemmed Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study
title_short Complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study
title_sort complications of unintentional dural puncture during labour epidural analgesia: a 10-year retrospective observational study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601237/
https://www.ncbi.nlm.nih.gov/pubmed/37880725
http://dx.doi.org/10.1186/s44158-023-00127-1
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