Alterations of the expression of TET2 and DNA 5-hmC predict poor prognosis in Myelodysplastic Neoplasms

BACKGROUND: Myelodysplastic Neoplasms (MDS) are clonal stem cell disorders characterized by ineffective hematopoiesis and progression to acute myeloid leukemia, myelodysplasia-related (AML-MR). A major mechanism of pathogenesis of MDS is the aberration of the epigenetic landscape of the hematopoieti...

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Detalles Bibliográficos
Autores principales: Seethy, Ashikh A., Pethusamy, Karthikeyan, Kushwaha, Tushar, Kumar, Gaurav, Talukdar, Joyeeta, Chaubey, Rekha, Sundaram, Udayakumar Dharmalingam, Mahapatra, Manoranjan, Saxena, Renu, Dhar, Ruby, Inampudi, Krishna K., Karmakar, Subhradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601240/
https://www.ncbi.nlm.nih.gov/pubmed/37884893
http://dx.doi.org/10.1186/s12885-023-11449-2

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