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Age-associated augmented renal clearance and low BMI trigger suboptimal vancomycin trough concentrations in children with haematologic diseases: data of 1453 paediatric patients from 2017 to 2022

BACKGROUND: It is usually difficult for the trough concentration of vancomycin to reach the recommended lower limit of 10 mg/L per the label dose in the paediatric population. Moreover, children with haematologic diseases who suffer from neutropenia are more likely to have lower exposure of vancomyc...

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Detalles Bibliográficos
Autores principales: Wang, Fengjiao, Zhou, Mi, Wang, Wenjuan, Zhu, Zengyan, Yan, Yinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601245/
https://www.ncbi.nlm.nih.gov/pubmed/37880633
http://dx.doi.org/10.1186/s12887-023-04288-4