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Case report: JAK1/2 inhibition with baricitinib in the treatment of STING-associated vasculopathy with onset in infancy

BACKGROUND: Gain-of-function mutations in STING1 (also known as TMEM173) which result in constitutive activation of STING, have been reported to cause STING-associated vasculopathy with onset in infancy (SAVI). Although a wider spectrum of associated manifestations and perturbations in disease onset...

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Detalles Bibliográficos
Autores principales: Wu, Jianqiang, Zhou, Qing, Zhou, Hua, Lu, Meiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601276/
https://www.ncbi.nlm.nih.gov/pubmed/37884945
http://dx.doi.org/10.1186/s12969-023-00916-6