Cargando…

Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model

BACKGROUND: MicroRNAs (miRNAs) are important post-transcriptional gene regulators controlling cellular lineage specification and differentiation during embryonic development, including the gastrointestinal system. However, miRNA-mediated regulatory mechanisms involved in early embryonic development...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hung, Yu-Han, Capeling, Meghan, Villanueva, Jonathan W., Kanke, Matt, Shanahan, Michael T., Huang, Sha, Cubitt, Rebecca, Rinaldi, Vera D., Schimenti, John C., Spence, Jason R., Sethupathy, Praveen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601309/ https://www.ncbi.nlm.nih.gov/pubmed/37884859 http://dx.doi.org/10.1186/s12864-023-09743-1

Ejemplares similares

Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival
por: Villanueva, Jonathan W., et al.
Publicado: (2022)

Biologically inspired approaches to enhance human organoid complexity
por: Holloway, Emily M., et al.
Publicado: (2019)

Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids
por: Capeling, Meghan M., et al.
Publicado: (2019)

Enteroendocrine Progenitor Cell–Enriched miR-7 Regulates Intestinal Epithelial Proliferation in an Xiap-Dependent Manner
por: Singh, Ajeet P., et al.
Publicado: (2019)

MiR-29 Regulates de novo Lipogenesis in the Liver and Circulating Triglyceride Levels in a Sirt1-Dependent Manner
por: Hung, Yu-Han, et al.
Publicado: (2019)

Gut Microbial Influences on the Mammalian Intestinal Stem Cell Niche
por: Peck, Bailey C. E., et al.
Publicado: (2017)

miRNA-214-3p stimulates carcinogen-induced mammary epithelial cell apoptosis in mammary cancer-resistant species
por: Harman, Rebecca M., et al.
Publicado: (2023)

Candidate master microRNA regulator of arsenic-induced pancreatic beta cell impairment revealed by multi-omics analysis
por: Todero, Jenna E., et al.
Publicado: (2022)

Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids
por: Hill, David R., et al.
Publicado: (2017)

Acquisition of NOTCH dependence is a hallmark of human intestinal stem cell maturation
por: Tsai, Yu-Hwai, et al.
Publicado: (2022)

Charting human development using a multi-endodermal organ atlas and organoid models
por: Yu, Qianhui, et al.
Publicado: (2021)

Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model
por: Hung, Yu-Han, et al.
Publicado: (2021)

Ozone‐induced changes in the murine lung extracellular vesicle small RNA landscape
por: Smith, Gregory J., et al.
Publicado: (2021)

Multiomic analysis of microRNA-mediated regulation reveals a proliferative axis involving miR-10b in fibrolamellar carcinoma
por: Francisco, Adam B., et al.
Publicado: (2022)

Synthetic Hydrogels for Human Intestinal Organoid Generation and Colonic Wound Repair
por: Cruz-Acuña, Ricardo, et al.
Publicado: (2017)

AGO HITS-CLIP reveals distinct miRNA regulation of white and brown adipose tissue identity
por: O'Connor, Sean, et al.
Publicado: (2021)

PGD(2) and CRTH2 counteract Type 2 cytokine–elicited intestinal epithelial responses during helminth infection
por: Oyesola, Oyebola O., et al.
Publicado: (2021)

Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids
por: Finkbeiner, Stacy R., et al.
Publicado: (2015)

Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis
por: Taylor, Henry J., et al.
Publicado: (2023)

Generation of renewable mouse intestinal epithelial cell monolayers and organoids for functional analyses
por: Moorefield, Emily C., et al.
Publicado: (2018)

Perfusion System for Modification of Luminal Contents of Human Intestinal Organoids and Realtime Imaging Analysis of Microbial Populations
por: Ginga, Nicholas J., et al.
Publicado: (2022)

Suspended hydrogel culture as a method to scale up intestinal organoids
por: Co, Julia Y., et al.
Publicado: (2023)

Single-Cell Analysis Reveals Unexpected Cellular Changes and Transposon Expression Signatures in the Colonic Epithelium of Treatment-Naïve Adult Crohn’s Disease Patients
por: Kanke, Matt, et al.
Publicado: (2022)

The Lumen of Human Intestinal Organoids Poses Greater Stress to Bacteria Compared to the Germ-Free Mouse Intestine: Escherichia coli Deficient in RpoS as a Colonization Probe
por: Barron, Madeline R., et al.
Publicado: (2020)

Transplanted human intestinal organoids: a resource for modeling human intestinal development
por: Singh, Akaljot, et al.
Publicado: (2023)

Clocking the Pace of Organoid Research
por: Spence, Jason R.
Publicado: (2017)

Intestinal organoids in farm animals
por: Beaumont, Martin, et al.
Publicado: (2021)

Standard: Human intestinal organoids
por: Wang, Yalong, et al.
Publicado: (2023)

Important Considerations for Studies of Circulating MicroRNAs in Clinical Samples
por: Hung, Yu-Han, et al.
Publicado: (2017)

Vertical sleeve gastrectomy induces enteroendocrine cell differentiation of intestinal stem cells through bile acid signaling
por: Kim, Ki-Suk, et al.
Publicado: (2022)

Culture and differentiation of rabbit intestinal organoids and organoid-derived cell monolayers
por: Kardia, Egi, et al.
Publicado: (2021)

Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice
por: Janeckova, Lucie, et al.
Publicado: (2019)

Intestinal Organoids—Current and Future Applications
por: Meneses, Andre M. C., et al.
Publicado: (2016)

Phenotypic landscape of intestinal organoid regeneration
por: Lukonin, Ilya, et al.
Publicado: (2020)

Human Intestinal Organoids: Promise and Challenge
por: Taelman, Jasin, et al.
Publicado: (2022)

Standard: Human intestinal cancer organoids
por: Lin, Hanqing, et al.
Publicado: (2023)

Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids
por: Abuaita, Basel H., et al.
Publicado: (2021)

Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice
por: Gomez, John C., et al.
Publicado: (2017)

Development of bioinformatics and multi-omics analyses in organoids
por: Ha, Doyeon, et al.
Publicado: (2023)

Taming the Wild West of Organoids, Enteroids, and Mini-Guts
por: Spence, Jason R.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ic5gb6v5airidosp88mqd5mj27