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Correspondence of Yolk Sac and Embryonic Genotypes in F0 Mouse CRISPants
CRISPR-mediated genome editing in vivo can be accompanied by prolonged stability of the Cas9 protein in mouse embryos. Then, genome edited variant alleles will be induced as long as Cas9 protein is active, and unmodified wildtype target loci are available. The corollary is that CRISPR-modified allel...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601497/ https://www.ncbi.nlm.nih.gov/pubmed/37885852 http://dx.doi.org/10.18103/mra.v11i6.3989 |