TGF-β1 Inhibition of ACE2 Mediated by miRNA Uncovers Novel Mechanism of SARS-CoV-2 Pathogenesis

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for COVID-19, utilizes receptor binding domain (RBD) of spike glycoprotein to interact with angiotensin (Ang)-converting enzyme 2 (ACE2). Altering ACE2 levels may affect entry of SARS-CoV-2 and recovery from COVID-19. Decr...

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Detalles Bibliográficos
Autores principales: Hejenkowska, Ewelina D., Mitash, Nilay, Donovan, Joshua E., Chandra, Anvita, Bertrand, Carol, De Santi, Chiara, Greene, Catherine M., Mu, Fangping, Swiatecka-Urban, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601633/
https://www.ncbi.nlm.nih.gov/pubmed/37579743
http://dx.doi.org/10.1159/000533606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601633/
https://www.ncbi.nlm.nih.gov/pubmed/37579743
http://dx.doi.org/10.1159/000533606

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