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TGF-β1 Inhibition of ACE2 Mediated by miRNA Uncovers Novel Mechanism of SARS-CoV-2 Pathogenesis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for COVID-19, utilizes receptor binding domain (RBD) of spike glycoprotein to interact with angiotensin (Ang)-converting enzyme 2 (ACE2). Altering ACE2 levels may affect entry of SARS-CoV-2 and recovery from COVID-19. Decr...
Autores principales: | Hejenkowska, Ewelina D., Mitash, Nilay, Donovan, Joshua E., Chandra, Anvita, Bertrand, Carol, De Santi, Chiara, Greene, Catherine M., Mu, Fangping, Swiatecka-Urban, Agnieszka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601633/ https://www.ncbi.nlm.nih.gov/pubmed/37579743 http://dx.doi.org/10.1159/000533606 |
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